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[Nutrition-physiological Properties of Frying Fats. 9. Overfeeding of Frying Fats and the Drug- and Toxic-substance-detoxicating Microsomal Enzyme-system of the Liver]

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Date 1976 Sep 1
PMID 987659
Citations 1
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Abstract

Long-term feeding of frying oil to male rats increases significantly the activity of the drug and toxic substances metabolizing microsomal enzyme system. This effect was also seen in the females, but only statistically insignificant.

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PMID: 6293212 DOI: 10.1007/BF02028812.

References
1.
Kracht K, Lang K, Henschel J . [Nutrition physiological effects of frying fats. 6. Histological findings in 2 generations of rats fed all their life with frying fats]. Z Ernahrungswiss. 1974; 13(3):132-42. DOI: 10.1007/BF02021372. View

2.
Lu A, Levin W . The resolution and reconstitution of the liver microsomal hydroxylation system. Biochim Biophys Acta. 1974; 344(2):205-40. DOI: 10.1016/0304-4157(74)90004-5. View

3.
CENTURY B . A role of the dietary lipid in the ability of phenobarbital to stimulate drug detoxification. J Pharmacol Exp Ther. 1973; 185(2):185-94. View

4.
Norred W, WADE A . Dietary fatty acid-induced alterations of hepatic microsomal drug metabolism. Biochem Pharmacol. 1972; 21(21):2887-97. DOI: 10.1016/0006-2952(72)90213-4. View

5.
Strobel H, Lu A, Heidema J, Coon M . Phosphatidylcholine requirement in the enzymatic reduction of hemoprotein P-450 and in fatty acid, hydrocarbon, and drug hydroxylation. J Biol Chem. 1970; 245(18):4851-4. View