Roy M, Horovitz A
Protein Sci. 2022; 31(5):e4298.
PMID: 35481656
PMC: 8994510.
DOI: 10.1002/pro.4298.
Crnjar A, Comitani F, Melis C, Molteni C
Interface Focus. 2019; 9(3):20180067.
PMID: 31065340
PMC: 6501341.
DOI: 10.1098/rsfs.2018.0067.
Bertozzi C, Zimmermann I, Engeler S, Hilf R, Dutzler R
PLoS Biol. 2016; 14(3):e1002393.
PMID: 26943937
PMC: 4778918.
DOI: 10.1371/journal.pbio.1002393.
Marotta C, Lester H, Dougherty D
Chem Biol. 2015; 22(8):1063-73.
PMID: 26211363
PMC: 4547686.
DOI: 10.1016/j.chembiol.2015.06.018.
Short C, Cao A, Wingfield M, Doers M, Jobe E, Wang N
Neuropharmacology. 2014; 91:157-68.
PMID: 25486620
PMC: 4332533.
DOI: 10.1016/j.neuropharm.2014.11.027.
Linear free-energy relationships and the dynamics of gating in the acetylcholine receptor channel.
Grosman C
J Biol Phys. 2013; 28(2):267-77.
PMID: 23345774
PMC: 3456670.
DOI: 10.1023/A:1019935832427.
Cholinergic modulation by opioid receptor ligands: potential application to Alzheimer's disease.
Motel W, Coop A, Cunningham C
Mini Rev Med Chem. 2012; 13(3):456-66.
PMID: 22931533
PMC: 3816933.
DOI: 10.2174/138955713804999784.
Design and control of acetylcholine receptor conformational change.
Jadey S, Purohit P, Bruhova I, Gregg T, Auerbach A
Proc Natl Acad Sci U S A. 2011; 108(11):4328-33.
PMID: 21368211
PMC: 3060238.
DOI: 10.1073/pnas.1016617108.
Temperature dependence of acetylcholine receptor channels activated by different agonists.
Gupta S, Auerbach A
Biophys J. 2011; 100(4):895-903.
PMID: 21320433
PMC: 3037575.
DOI: 10.1016/j.bpj.2010.12.3727.
Glycine hinges with opposing actions at the acetylcholine receptor-channel transmitter binding site.
Purohit P, Auerbach A
Mol Pharmacol. 2010; 79(3):351-9.
PMID: 21115636
PMC: 3061369.
DOI: 10.1124/mol.110.068767.
In vitro and in vivo characterization of a novel negative allosteric modulator of neuronal nAChRs.
Abdrakhmanova G, Blough B, Nesloney C, Navarro H, Damaj M, Carroll F
Neuropharmacology. 2010; 59(6):511-7.
PMID: 20633568
PMC: 2998338.
DOI: 10.1016/j.neuropharm.2010.07.006.
Acetylcholine receptor channels activated by a single agonist molecule.
Jha A, Auerbach A
Biophys J. 2010; 98(9):1840-6.
PMID: 20441747
PMC: 2862204.
DOI: 10.1016/j.bpj.2010.01.025.
Energetics of gating at the apo-acetylcholine receptor transmitter binding site.
Purohit P, Auerbach A
J Gen Physiol. 2010; 135(4):321-31.
PMID: 20351060
PMC: 2847916.
DOI: 10.1085/jgp.200910384.
Energy and structure of the M2 helix in acetylcholine receptor-channel gating.
Jha A, Purohit P, Auerbach A
Biophys J. 2009; 96(10):4075-84.
PMID: 19450479
PMC: 2712209.
DOI: 10.1016/j.bpj.2009.02.030.
Unliganded gating of acetylcholine receptor channels.
Purohit P, Auerbach A
Proc Natl Acad Sci U S A. 2008; 106(1):115-20.
PMID: 19114650
PMC: 2629231.
DOI: 10.1073/pnas.0809272106.
Acetylcholine receptor gating at extracellular transmembrane domain interface: the cys-loop and M2-M3 linker.
Jha A, Cadugan D, Purohit P, Auerbach A
J Gen Physiol. 2007; 130(6):547-58.
PMID: 18040057
PMC: 2151658.
DOI: 10.1085/jgp.200709856.
Conformational dynamics of the alphaM3 transmembrane helix during acetylcholine receptor channel gating.
Cadugan D, Auerbach A
Biophys J. 2007; 93(3):859-65.
PMID: 17513382
PMC: 1913136.
DOI: 10.1529/biophysj.107.105171.
Desensitization contributes to the synaptic response of gain-of-function mutants of the muscle nicotinic receptor.
Elenes S, Ni Y, Cymes G, Grosman C
J Gen Physiol. 2006; 128(5):615-27.
PMID: 17074980
PMC: 2151585.
DOI: 10.1085/jgp.200609570.
A speed limit for conformational change of an allosteric membrane protein.
Chakrapani S, Auerbach A
Proc Natl Acad Sci U S A. 2004; 102(1):87-92.
PMID: 15618401
PMC: 544059.
DOI: 10.1073/pnas.0406777102.
Free-energy landscapes of ion-channel gating are malleable: changes in the number of bound ligands are accompanied by changes in the location of the transition state in acetylcholine-receptor channels.
Grosman C
Biochemistry. 2003; 42(50):14977-87.
PMID: 14674774
PMC: 1463891.
DOI: 10.1021/bi0354334.
