» Articles » PMID: 9032401

Mapping and Characterization of the Origin of DNA Replication of Porcine Circovirus

Overview
Journal J Virol
Date 1997 Mar 1
PMID 9032401
Citations 55
Authors
Affiliations
Soon will be listed here.
Abstract

The origin of DNA replication of porcine circovirus (PCV) was mapped to a 111-bp fragment. On top of a hairpin, a nonanucleotide (TAGTATTAC) homologous to nonanucleotides of other viruses was identified. Mutation of this element abolishes replication. PCV may be related to a virus family characterized by single-stranded circular DNA genomes, rolling-circle replication, and homology of their rep proteins.

Citing Articles

Aquatic circoviruses: emerging pathogens in global aquaculture - from discovery to disease management.

Wang Y, Guo C, He J J Virol. 2024; 99(1):e0173724.

PMID: 39670743 PMC: 11784310. DOI: 10.1128/jvi.01737-24.


Development of a novel PCV2 and PCV3 vaccine using virus-like vesicles incorporating Venezuelan equine encephalomyelitis virus-containing vesicular stomatitis virus glycoprotein.

Wang Y, Su M, Huang Y, Ren J, Niu S, Zhao Y Front Vet Sci. 2024; 11:1359421.

PMID: 38840631 PMC: 11150706. DOI: 10.3389/fvets.2024.1359421.


Development of gold Immunochromatographic assay strip based on specific polyclonal antibodies against capsid protein for rapid detection of porcine circovirus 2 in Zhejiang province, China.

Ding H, Shen Y, Gao Y, Wu S, Xie C, Sun H BMC Vet Res. 2022; 18(1):373.

PMID: 36253821 PMC: 9578217. DOI: 10.1186/s12917-022-03471-6.


Rapid detection of porcine circovirus type 4 multienzyme isothermal rapid amplification.

Li Y, Zhao Y, Li C, Yang K, Li Z, Shang W Front Vet Sci. 2022; 9:949172.

PMID: 35968022 PMC: 9366244. DOI: 10.3389/fvets.2022.949172.


Diversity of CRESS DNA Viruses in Squamates Recapitulates Hosts Dietary and Environmental Sources of Exposure.

Capozza P, Lanave G, Diakoudi G, Pellegrini F, Cardone R, Vasinioti V Microbiol Spectr. 2022; 10(3):e0078022.

PMID: 35616383 PMC: 9241739. DOI: 10.1128/spectrum.00780-22.


References
1.
Heyraud F, Matzeit V, Kammann M, Schaefer S, Schell J, Gronenborn B . Identification of the initiation sequence for viral-strand DNA synthesis of wheat dwarf virus. EMBO J. 1993; 12(11):4445-52. PMC: 413744. DOI: 10.1002/j.1460-2075.1993.tb06130.x. View

2.
Koonin E, Ilyina T . Computer-assisted dissection of rolling circle DNA replication. Biosystems. 1993; 30(1-3):241-68. DOI: 10.1016/0303-2647(93)90074-m. View

3.
Stanley J . Analysis of African cassava mosaic virus recombinants suggests strand nicking occurs within the conserved nonanucleotide motif during the initiation of rolling circle DNA replication. Virology. 1995; 206(1):707-12. DOI: 10.1016/s0042-6822(95)80093-x. View

4.
Boevink P, Chu P, Keese P . Sequence of subterranean clover stunt virus DNA: affinities with the geminiviruses. Virology. 1995; 207(2):354-61. DOI: 10.1006/viro.1995.1094. View

5.
Schumacher S, Laufs J, Schaefer S, Schell J, Gronenborn B . Determination of the origin cleavage and joining domain of geminivirus Rep proteins. Nucleic Acids Res. 1995; 23(6):910-6. PMC: 306784. DOI: 10.1093/nar/23.6.910. View