Rat Bile As a Convenient Source of Secretory IgA and Free Secretory Component

Overview

Journal Eur J Immunol

Specialty Allergy & Immunology

Date 1977 Aug 1

PMID 902683

Citations 38

Authors

G D Jackson

J P Vaerman

Affiliations

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Abstract

Rat hepatic bile contains three proteins as major constituents: secretory IgA (SIgA), free secretory component (FSC) and albumin. Traces of alpha-macroglobulin, transferrin, IgG and IgM are also detectable. The bile duct daily pours between 5-12 mg each of SIgA and FSC into the rat duodenum. The origin and function of these proteins in bile may represent important clues in the understanding of the SIgA system.

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