Quasispecies in Wild-type Tula Hantavirus Populations

Overview

Journal J Virol

Publisher American Society for Microbiology

Date 1996 Dec 1

PMID 8971044

Citations 16

Authors

A Plyusnin

Y Cheng

H Lehvaslaiho

A Vaheri

Affiliations

Soon will be listed here.

Abstract

Tula virus (TUL) is a recently detected hantavirus carried by European common voles. Reverse transcriptase PCR cloning was used to study TUL S segment/N protein quasispecies. Both the distribution and character of mutations observed in three mutant spectra indicated limited selection at the protein level. At least 8% of the mutations were neutral or well tolerated; fixation of such mutations may play a role in TUL evolution in its natural host.

Citing Articles

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New Genetic Lineage of Tula Hantavirus in Microtus arvalis obscurus in Eastern Kazakhstan.

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