Lymphocyte Surface IgD and IgM in Non-human Primates

Overview

Journal Int Arch Allergy Appl Immunol

Publisher Karger

Specialty Allergy & Immunology

Date 1976 Jan 1

PMID 819380

Citations 13

Authors

L N Martin

G A Leslie

R Hindes

Affiliations

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Abstract

IgD was detected on the surface of peripheral blood lymphocytes of five non-human primate species by direct immunofluorescence. The percentages of lymphocytes with surface IgD or IgM were comparable to the percentages reported for humans. The presence of IgD on the surface of rhesus monkey lymphocytes was confirmed by SDS-polyacrylamide gel electrophoresis of immunoprecipitated 125I cell surface protein. Reduced surface IgD was resolved into a light chain component and a heavy chain component whose mobility was identical to that of mu-chain under the condition used.

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