Examination of Streptococcus Mutans for Immunoglobulin G Fc Reactivity

Overview

Journal Infect Immun

Publisher American Society for Microbiology

Specialty Allergy & Immunology

Date 1981 Dec 1

PMID 7333670

Citations 1

Authors

C Shea

J J Ferretti

Affiliations

Soon will be listed here.

Abstract

Representative strains of oral streptococci were tested for Fc immunoglobulin G (IgG) reactivity by two different techniques, agglutination of rabbit-IgG sensitized sheep erythrocytes and uptake of human and rabbit 125I-radiolabeled IgG. None of the S. mutans serotypes a through e reacted with the Fc region of either human or rabbit IgG. Additionally, other streptococci such as S. sanguis, S. salivarius, S. faecalis, and S. mitis failed to show appreciable Fc reactivity as assayed by these techniques. The group A, C, and G streptococci, previously shown to possess Fc reactivity, proved to be reactive in these experiments, as did a protein A-containing strain of Staphylococcus aureus.

Citing Articles

Immunochemistry of the Streptococcus mutans BHT cell membrane: detection of determinants cross-reactive with human heart tissue.

Ayakawa G, Siegel J, Crowley P, Bleiweis A Infect Immun. 1985; 48(2):280-6.

PMID: 3886543 PMC: 261301. DOI: 10.1128/iai.48.2.280-286.1985.

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