Antitumor Agents. 49 Tricin, Kaempferol-3-O-beta-D-glucopyranoside and (+)-nortrachelogenin, Antileukemic Principles from Wikstroemia Indica

Overview

Journal J Nat Prod

Date 1981 Sep 1

PMID 7320737

Citations 17

Authors

K H Lee

K TAGAHARA

H Suzuki

R Y Wu

M Haruna

I H Hall

H C Huang

K Ito

T Iida

J S Lai

Affiliations

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Abstract

Bioassay-directed isolation of the antitumor extract of Wikstroemia indica (Thymelaeaceae) has led to the characterization of tricin, kaempferol-3-O-beta-D-glucopyranoside, and (+)-nortrachelogenin as the major antileukemic constituents. In addition, daphnoretin was identified as the potent antitumor principle in vivo against the Ehrlich ascites carcinoma growth in mice.

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