I H Hall
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Explore the profile of I H Hall including associated specialties, affiliations and a list of published articles.
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294
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842
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Recent Articles
1.
Chapman Jr J, Wyrick S, Maguire J, Cocolas G, Hall I
Pharm Res
. 2013 Nov;
1(6):267-9.
PMID: 24277360
A number of substituted phthalimide, 1, 8-naphthalimide, succinimide and glutarimide derivatives demonstrated significant hypolipidemic activity at 20 mg/kg/ day, I.P. after 16 days dosing. The N-(n-pentyl) succinimide proved to be...
2.
Voorstad P, Cocolas G, Hall I
Pharm Res
. 2013 Nov;
1(6):250-5.
PMID: 24277357
3-Immophthalimidine (3-imino-2,3-dihydroisoindol-l-one) was examined for its hypolipidemic activity in rodents as a chemical modification of the phthalimide nucleus. Administration of 3-iminophthalimidine for 16 days, at 20 mg/kg/day, demonstrated potent hypolipidemic...
3.
Hall I, Chapman Jr J, Gilbert C
Pharm Res
. 2013 Nov;
1(2):63-8.
PMID: 24277214
A series of benzenetricarboxylic acids was shown to be potent hypolipidemic agents in rodents. Terephthalic acid proved to be one of the more potent agents, lowering serum cholesterol 42% and...
4.
Hall I, Wyrick S, Voorstad P, Dubey A
Pharm Res
. 2013 Nov;
1(1):28-32.
PMID: 24277181
N-(p-Chlorobenzoyl)-sulfamate was observed to produce potent hypolipidemic activity in rodents at 10 to 60 mg/kg/day. Liver phosphatidate phosphohydrolase and sn-glycerol-3-phosphate acyl transferase activities were suppressed by the agent in vitro...
5.
Hall I, Williams Jr W, Rhyne K, Knowles M
Pharm Res
. 2013 Nov;
2(5):233-8.
PMID: 24272843
2-Furoic acid, 3-furoic acid, 3,4-furan dicarboxylic acid and furyl-acrylic acid were evaluated for hypolipidemic activity in mice and rats. 2-Furoic acid was the most potent agent of the four tested,...
6.
The synthesis of homophthalimide and related derivatives and their hypolipidemic activity in rodents
Murthy A, Chapman Jr J, Wyrick S, Hall I
Pharm Res
. 2013 Nov;
3(5):286-9.
PMID: 24271711
Homophthalimide and a series of N-alkyl-substituted derivatives were investigated to determine their ability to lower serum cholesterol and triglyceride levels in mice. At 20 mg/kg/day these agents were equally potent...
7.
Murthy A, Hall I, Chapman Jr J, Rhyne K, Wyrick S
Pharm Res
. 2013 Nov;
3(2):93-101.
PMID: 24271467
A series of substituted 2,3-dihydrophthalazine-l,4-dione derivatives as well as the corresponding N,N-diaminophthalamides were prepared and were demonstrated to have potent hypolipidemic activity, lowering both serum triglyceride and cholesterol levels significantly...
8.
Hall I, Hall E, Miller 3rd M, Sood A, Spielvogel B
Amino Acids
. 2013 Nov;
4(3):287-302.
PMID: 24190609
The purpose of this study was to establish the efficacy and mode of action of peptide boron derivatives as antineoplastic agents and to evaluate their safety in vivo. Boron-containing phenylalanine...
9.
Karthikeyan S, Sood A, Tomasz J, Spielvogel B, Hall I
Amino Acids
. 2013 Nov;
8(4):323-35.
PMID: 24186510
This work is an extension of our previous work (Hall et al., 1993) on the synthesis and cytotoxic activity of boronated peptides. The aim of this work was to carry...
10.
Miller M, Sood A, Spielvogel B, Hall I
Met Based Drugs
. 2008 May;
6(6):337-44.
PMID: 18475910
The boronated aromatic amino acids were shown to be potent hypolipidemic agents in mice lowering both serum cholesterol and triglycerides after 16 days. Selective compounds were as effective as the...