A New Approach in the Evaluation of Chromosome Variants in Man, III. Pairs with Established Q or C Variable Sites

Overview

Journal Hum Genet

Specialty Genetics

Date 1980 Jan 1

PMID 7203466

Authors

S Oka

Y NAKAGOME

J Azumi

E Matsunaga

Y Igarashi

Affiliations

Soon will be listed here.

Abstract

A new approach is proposed for the evaluation of chromosome variants, which uses a scanning microdensitometer in the determination of the area of a variant. Results are assigned into five classes based on the difference from an average in terms of standard deviation. In the first two papers of the present series, results obtained in C variants of 1,9, and 16 and LBA variants in 12 pairs lacking an established variable site (e.g., nos. 2, 5, 6, etc.) were described. In the present communication, results obtained in pairs with a known Q-variable site are described. When a variable region outside of +/- 1 SD of the average is defined as a variant, 9, 11, 7, 10, and 10 variants are detected in pairs 13, 14, 15, 21, and 22, respectively, from 12 individuals by means of LBA preparations, in addition to Q variants, which can be detected by the standard QFQ technique.

References

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