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Does Rifampicin Increase Serum Levels of Testosterone and Oestradiol by Inducing Sex Hormone Binding Globulin Capacity?

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Specialty Pharmacology
Date 1981 Sep 1
PMID 7197544
Citations 9
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References
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Van Der Meulen A . An unusual case of massive hypertrophy of the breasts. S Afr Med J. 1974; 48(34):1465-6. View

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Gustafsson J . Regulation and substrate specificity of a steroid sulfate-specific hydroxylase system in female rat liver microsomes. J Biol Chem. 1975; 250(9):3451-8. View

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Bolt H, Kappus H, Bolt M . Effect of rifampicin treatment on the metabolism of oestradiol and 17alpha-ethinyloestradiol by human liver microsomes. Eur J Clin Pharmacol. 1975; 8(5):301-7. DOI: 10.1007/BF00562654. View

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Kjeld J, Puah C, JOPLIN G . Changed levels of endogenous sex steroids in women on oral contraceptives. Br Med J. 1976; 2(6048):1354-6. PMC: 1690292. DOI: 10.1136/bmj.2.6048.1354. View

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Bolt H, Bolt M, Kappus H . Interaction of rifampicin treatment with pharmacokinetics and metabolism of ethinyloestradiol in man. Acta Endocrinol (Copenh). 1977; 85(1):189-197. DOI: 10.1530/acta.0.0850189. View