A R Boobis
Overview
Explore the profile of A R Boobis including associated specialties, affiliations and a list of published articles.
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Articles
212
Citations
1675
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0
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Recent Articles
1.
Kumar V, Boobis A, Moretto A
Food Chem Toxicol
. 2020 Jul;
144:111607.
PMID: 32687857
No abstract available.
2.
Rotter S, Beronius A, Boobis A, Hanberg A, van Klaveren J, Luijten M, et al.
Crit Rev Toxicol
. 2019 Jan;
48(9):796-814.
PMID: 30632445
This article reviews the current legislative requirements for risk assessment of combined exposure to multiple chemicals via multiple exposure routes, focusing on human health and particularly on food-related chemicals. The...
3.
Patel S, Bhambra U, Charalambous M, David R, Edwards R, Lightfoot T, et al.
Br J Cancer
. 2014 Oct;
111(12):2287-96.
PMID: 25333344
Background: The pro-inflammatory cytokine interleukin-6 (IL6) promotes colorectal cancer (CRC) development. It is also known to regulate cytochrome P450 (CYP450) enzymes, which are involved in CRC tumour initiation and promotion...
4.
Boobis A
Environ Toxicol Pharmacol
. 2011 Jul;
2(2-3):161-3.
PMID: 21781720
In assessing interindividual variability in metabolic activation, the toxic metabolite is often too unstable for conventional analysis. Possible alternatives include a stable product of the reactive metabolite e.g. cysteinyl derivatives...
5.
Boobis A, Kahn G, Whyte C, Brodie M, Davies D
Biochem Pharmacol
. 2010 Nov;
30(17):2451-6.
PMID: 21043244
Human and rat liver microsomal fractions exhibit non-linear Michaelis-Menten kinetics in the O-deethylation of both phenacetin and 7-ethoxycoumarin. Comparison of various models indicated that the data were best described by...
6.
7.
Chiu T, Koh Y, Paterakis N, Boobis A, Cartmell E, Richards K, et al.
J Chromatogr A
. 2009 May;
1216(24):4923-6.
PMID: 19426986
Optimization of an analytical method for determination of steroid estrogens, through minimizing sample size, resulted in recoveries >84%, with relative standard deviations <3% and demonstrated the significance of sample size...
8.
Fang M, Boobis A, Edwards R
Food Chem Toxicol
. 2007 Jul;
45(11):2126-37.
PMID: 17602814
The neurotoxicity of chemicals to humans is difficult to monitor as there are no suitable methods of detecting early neuronal dysfunction. Here, a proof of principle study was designed to...
9.
Bull S, Fletcher K, Boobis A, Battershill J
Mutagenesis
. 2006 Mar;
21(2):93-103.
PMID: 16567350
A systematic review of the literature has been conducted and studies reporting investigations of genotoxicity biomarkers in pesticide workers have been assessed with view to establishing whether there was evidence...
10.
Gilbert E, Edwards R, Boobis A, Rose S, Jenner P
J Neural Transm (Vienna)
. 2003 Oct;
110(10):1091-101.
PMID: 14523622
Genetic susceptibility to toxin action leading to nigral cell degeneration in Parkinson's disease (PD) may be dictated by the activity of P450 enzymes in brain. In adult rat brain only...