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Pyridinium-2-azo-p-dimethylaniline Chromophore, a New Chromogenic Cephalosporin for Rapid Beta-lactamase Testing

Overview
Journal Antimicrob Agents Chemother
Publisher American Society for Microbiology
Specialty Pharmacology
Date 1982 Jul 1
PMID 6982024
Citations 5
Authors
J H Jorgensen
S A Crawford
G A Alexander
Affiliations
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Abstract

A new chromogenic cephalosporin, pyridinium-2-azo-p-dimethylaniline chromophore, was evaluated for use in a rapid paper strip or tube test for the detection of beta-lactamases from a variety of microorganisms. A 1-min pyridinium-2-azo-p-dimethylaniline chromophore paper strip test was found to be a convenient and accurate method for the detection of beta-lactamase-producing strains of Haemophilus influenzae and Neisseria gonorrhoeae, although it could not be relied upon to detect beta-lactamases produced by staphylococci, enteric organisms, or Bacteroides fragilis.

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References
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