Pasteurella Haemolytica Cytotoxin: Production by Recognized Serotypes and Neutralization by Type-specific Rabbit Antisera

Overview

Journal Am J Vet Res

Specialty Veterinary Medicine

Date 1983 Apr 1

PMID 6869971

Citations 14

Authors

P E Shewen

B N Wilkie

Affiliations

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Abstract

A sterile culture supernatant from each of the 12 recognized serotypes of Pasteurella haemolytica was toxic to bovine alveolar macrophages when assayed by 51Cr release. Types appeared to differ in their ability to liberate cytotoxin, although this may have reflected strain variation rather than serotype-related differences. Toxicity was partially neutralized by type-specific rabbit antisera, with neutralization of the homologous toxin being more effective than that of the heterologous serotype.

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Serum IgG response in calves to the putative pneumonic virulence factor Gs60 of Mannheimia haemolytica A1.

Orouji S, Hodgins D, Lo R, Shewen P Can J Vet Res. 2013; 76(4):292-300.

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Cho H, Bohac J, Yates W, Bielefeldt Ohmann H Can J Comp Med. 1984; 48(2):151-5.

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