Pasteurella Haemolytica Cytotoxin Neutralizing Activity in Sera from Ontario Beef Cattle

Overview

Journal Can J Comp Med

Specialty Veterinary Medicine

Date 1983 Oct 1

PMID 6667433

Citations 14

Authors

P E Shewen

B N Wilkie

Affiliations

Soon will be listed here.

Abstract

A random sample of sera obtained from cattle necropsied as part of the Bruce County Beef Project in 1980-81 was assayed for the ability to neutralize the cytotoxin of Pasteurella haemolytica A1. Cattle dying of fibrinous pneumonia had significantly lower neutralizing activity in serum than cattle which died for reasons other than pneumonia. Activity in pneumonic cattle was also lower than the mean of twelve samples randomly chosen from sera of cattle bled on entry to feedlots in the fall of 1979. A role for the toxin neutralizing response in resistance to pneumonic pasteurellosis is proposed.

Citing Articles

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Comparison of a multivalent viral vaccine program versus a univalent viral vaccine program on animal health, feedlot performance, and carcass characteristics of feedlot calves.

Schunicht O, Booker C, Jim G, Guichon P, Wildman B, Hill B Can Vet J. 2003; 44(1):43-50.

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Seroepidemiology of undifferentiated fever in feedlot calves in western Canada.

Booker C, Guichon P, Jim G, Schunicht O, Harland R, Morley P Can Vet J. 1999; 40(1):40-8.

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Molecular analysis of the leukotoxin determinants from Pasteurella haemolytica serotypes 1 to 16.

Burrows L, Lo R Infect Immun. 1993; 61(12):5001-7.

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Dissociation of cytolysis and monokine release by bovine mononuclear phagocytes incubated with Pasteurella haemolytica partially purified leukotoxin and lipopolysaccharide.

Stevens P, Czuprynski C Can J Vet Res. 1995; 59(2):110-7.

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References

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