A DNA Sequence Analysis Package for the IBM Personal Computer

Overview

Journal Nucleic Acids Res

Publisher Oxford University Press

Specialty Biochemistry

Date 1984 Jan 11

PMID 6546433

Citations 25

Authors

L M Lagrimini

S T Brentano

J E Donelson

Affiliations

Soon will be listed here.

Abstract

We present here a collection of DNA sequence analysis programs, called "PC Sequence" (PCS), which are designed to run on the IBM Personal Computer (PC). These programs are written in IBM PC compiled BASIC and take full advantage of the IBM PC's speed, error handling, and graphics capabilities. For a modest initial expense in hardware any laboratory can use these programs to quickly perform computer analysis on DNA sequences. They are written with the novice user in mind and require very little training or previous experience with computers. Also provided are a text editing program for creating and modifying DNA sequence files and a communications program which enables the PC to communicate with and collect information from mainframe computers and DNA sequence databases.

Citing Articles

Characterization of the 1.35 kilobase DNA repeat unit containing the conserved 35 nucleotides at the 5'-termini of variable surface glycoprotein mRNAs in Trypanosoma brucei.

Dorfman D, Donelson J Nucleic Acids Res. 1984; 12(12):4907-20.

PMID: 6330689 PMC: 318888. DOI: 10.1093/nar/12.12.4907.

Expression of antigenic regions of a trypanosome variable surface glycoprotein in E. coli using Bal-31 nuclease digestion.

Lenardo M, Brentano S, Donelson J Nucleic Acids Res. 1984; 12(11):4637-52.

PMID: 6204274 PMC: 318864. DOI: 10.1093/nar/12.11.4637.

Fusion protein of the paramyxovirus simian virus 5: nucleotide sequence of mRNA predicts a highly hydrophobic glycoprotein.

PATERSON R, Harris T, Lamb R Proc Natl Acad Sci U S A. 1984; 81(21):6706-10.

PMID: 6093114 PMC: 391999. DOI: 10.1073/pnas.81.21.6706.

Identification and predicted sequence of a previously unrecognized small hydrophobic protein, SH, of the paramyxovirus simian virus 5.

Hiebert S, PATERSON R, Lamb R J Virol. 1985; 55(3):744-51.

PMID: 4020965 PMC: 255058. DOI: 10.1128/JVI.55.3.744-751.1985.

The 5.8S ribosomal RNA gene of Trypanosoma brucei: structural and transcriptional studies.

Dorfman D, Lenardo M, Reddy L, Van der Ploeg L, Donelson J Nucleic Acids Res. 1985; 13(10):3533-49.

PMID: 4011434 PMC: 341257. DOI: 10.1093/nar/13.10.3533.

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