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» Articles » PMID: 6543108

Effect of Aztreonam on Throat and Stool Flora of Cancer Patients

Overview
Journal Antimicrob Agents Chemother
Publisher American Society for Microbiology
Specialty Pharmacology
Date 1984 Dec 1
PMID 6543108
Citations 7
Authors
P G Jones
G P Bodey
E A Swabb
B Rosenbaum
Affiliations
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Abstract

Eighteen patients with hematological malignancies received aztreonam in one of two dosing regimens, 1 or 2 g every 8 h for a total of 7 to 9 days. Throat and stool cultures were obtained before and during treatment with aztreonam. Aztreonam had little effect on the predominant throat flora. In contrast, facultatively anaerobic gram-negative bacilli were markedly decreased in stools during the administration of aztreonam. Strict anaerobes in the stool were variably affected by aztreonam.

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