Genetic Studies on the Beta Subunit of Escherichia Coli RNA Polymerase. VI. A Redundant Region in the Beta Polypeptide

Overview

Journal Mol Gen Genet

Specialties Genetics
Molecular Biology

Date 1984 Jan 1

PMID 6384732

Citations 12

Authors

V Nene

R E Glass

Affiliations

Soon will be listed here.

Abstract

A single species of RNA polymerase is responsible for the transcription of genetic material in Escherichia coli; and, each component of this essential enzyme is encoded by a single gene. Nevertheless, we report the characterisation of a viable deletion mutant lacking about 165 bp in the region coding for residues 965 to 1143 of the beta subunit of this enzyme. The foreshortened beta polypeptide appears to function as normal, suggesting that this region is, in fact, non-essential with regard to the usual functions of E. coli RNA polymerase.

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