Characterization of a Highly Repetitive Family of DNA Sequences in the Mouse

Overview

Journal Nucleic Acids Res

Publisher Oxford University Press

Specialty Biochemistry

Date 1982 Aug 25

PMID 6290999

Citations 32

Authors

T G Fanning

Affiliations

Soon will be listed here.

Abstract

A large proportion (0.5-1%) of total mouse DNA is cleaved by Bam HI into fragments whose size is about 500 base pairs. A cloned member of this repetitive family of DNA sequences (BAM5 family) was sequenced by the dideoxy chain termination procedure and shown to contain 507 base pairs. The sequence exhibited no unusual or remarkable features. Repetitive sequences complementary to the cloned BAM5 fragment were found in rat DNA, but not in feline or human DNA. Restriction mapping suggested that many BAM5 sequences were components of much larger repetitive DNAs which were scattered throughout the mouse genome. The BAM5 sequences within the larger repetitive DNAs did not appear to be arranged tandemly or as members of scrambled tandem repeats. RNA homologous to the cloned BAM5 sequence was detected in cultured mouse cells, but not in cultured rat cells.

Citing Articles

Interspersed repetitive L1 family is differentially transcribed during the murine thymus ontogeny.

Raschella G, Mosiello L, Negroni A, Adorini L, Romeo A Cytotechnology. 2012; 1(1):65-71.

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Looking for relationships between the most repeated dispersed DNA sequences in the mouse: small R elements are found associated consistently with long MIF repeats.

Bennett K, Hastie N EMBO J. 1984; 3(2):467-72.

PMID: 6714224 PMC: 557367. DOI: 10.1002/j.1460-2075.1984.tb01829.x.

A large interspersed repeat found in mouse DNA contains a long open reading frame that evolves as if it encodes a protein.

Martin S, Voliva C, Burton F, Edgell M, HUTCHISON 3rd C Proc Natl Acad Sci U S A. 1984; 81(8):2308-12.

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The L1Md long interspersed repeat family in the mouse: almost all examples are truncated at one end.

Voliva C, Jahn C, Comer M, HUTCHISON 3rd C, Edgell M Nucleic Acids Res. 1983; 11(24):8847-59.

PMID: 6324106 PMC: 326629. DOI: 10.1093/nar/11.24.8847.

The Bam repeats of the mouse genome belong in several superfamilies the longest of which is over 9 kb in size.

Bernardi G Nucleic Acids Res. 1984; 12(3):1593-608.

PMID: 6322110 PMC: 318601. DOI: 10.1093/nar/12.3.1593.

References

Britten R, Davidson E . Gene regulation for higher cells: a theory. Science. 1969; 165(3891):349-57. DOI: 10.1126/science.165.3891.349. View

Southern E . Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol. 1975; 98(3):503-17. DOI: 10.1016/s0022-2836(75)80083-0. View

Rigby P, Dieckmann M, Rhodes C, Berg P . Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I. J Mol Biol. 1977; 113(1):237-51. DOI: 10.1016/0022-2836(77)90052-3. View

SANGER F, Nicklen S, Coulson A . DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci U S A. 1977; 74(12):5463-7. PMC: 431765. DOI: 10.1073/pnas.74.12.5463. View

Gronenborn B, Messing J . Methylation of single-stranded DNA in vitro introduces new restriction endonuclease cleavage sites. Nature. 1978; 272(5651):375-7. DOI: 10.1038/272375a0. View

Tabak H, Flavell R . A method for the recovery of DNA from agarose gels. Nucleic Acids Res. 1978; 5(7):2321-32. PMC: 342166. DOI: 10.1093/nar/5.7.2321. View

Pedersen P, Greenawalt J, REYNAFARJE B, Hullihen J, Decker G, SOPER J . Preparation and characterization of mitochondria and submitochondrial particles of rat liver and liver-derived tissues. Methods Cell Biol. 1978; 20:411-81. DOI: 10.1016/s0091-679x(08)62030-0. View

Davidson E, Britten R . Regulation of gene expression: possible role of repetitive sequences. Science. 1979; 204(4397):1052-9. DOI: 10.1126/science.451548. View

Lane D, Gardner R . Second EcoRI fragment of F capable of self-replication. J Bacteriol. 1979; 139(1):141-51. PMC: 216839. DOI: 10.1128/jb.139.1.141-151.1979. View

10.

Fry K, Brutlag D . Detection and resolution of closely related satellite DNA sequences by molecular cloning. J Mol Biol. 1979; 135(3):581-93. DOI: 10.1016/0022-2836(79)90165-7. View

11.

Doolittle W, Sapienza C . Selfish genes, the phenotype paradigm and genome evolution. Nature. 1980; 284(5757):601-3. DOI: 10.1038/284601a0. View

12.

Orgel L, Crick F . Selfish DNA: the ultimate parasite. Nature. 1980; 284(5757):604-7. DOI: 10.1038/284604a0. View

13.

Jelinek W, Toomey T, Leinwand L, Duncan C, Biro P, Choudary P . Ubiquitous, interspersed repeated sequences in mammalian genomes. Proc Natl Acad Sci U S A. 1980; 77(3):1398-402. PMC: 348502. DOI: 10.1073/pnas.77.3.1398. View

14.

Hanahan D, Meselson M . Plasmid screening at high colony density. Gene. 1980; 10(1):63-7. DOI: 10.1016/0378-1119(80)90144-4. View

15.

Heidecker G, Messing J, Gronenborn B . A versatile primer for DNA sequencing in the M13mp2 cloning system. Gene. 1980; 10(1):69-73. DOI: 10.1016/0378-1119(80)90145-6. View

16.

Cheng S, SCHILDKRAUT C . A family of moderately repetitive sequences in mouse DNA. Nucleic Acids Res. 1980; 8(18):4075-90. PMC: 324220. DOI: 10.1093/nar/8.18.4075. View

17.

Krayev A, Kramerov D, Skryabin K, Ryskov A, Bayev A, Georgiev G . The nucleotide sequence of the ubiquitous repetitive DNA sequence B1 complementary to the most abundant class of mouse fold-back RNA. Nucleic Acids Res. 1980; 8(6):1201-15. PMC: 323986. DOI: 10.1093/nar/8.6.1201. View

18.

Thomas P . Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose. Proc Natl Acad Sci U S A. 1980; 77(9):5201-5. PMC: 350025. DOI: 10.1073/pnas.77.9.5201. View

19.

Fanning T, Puma J, Cardiff R . Selective amplification of mouse mammary tumor virus in mammary tumors of GR mice. J Virol. 1980; 36(1):109-14. PMC: 353620. DOI: 10.1128/JVI.36.1.109-114.1980. View

20.

Manuelidis L . Novel classes of mouse repeated DNAs. Nucleic Acids Res. 1980; 8(15):3247-58. PMC: 324149. DOI: 10.1093/nar/8.15.3247. View