Quercetin Enhances Water Transport in Toad Bladder

Overview

Journal Experientia

Specialty Science

Date 1981 Jul 15

PMID 6268437

Citations 4

Authors

A Grosso

R C de Sousa

Affiliations

Soon will be listed here.

Abstract

A highly significant enhancement of the hydrosmotic actions both of vasopressin and of exogenous cAMP was seen in the presence of quercetin. The hypothesis is advanced that quercetin affects the intracellular coupling between Ca++ in cAMP.

Citing Articles

Osmotic water flow across the abdominal skin of the toad bufo marinus: effect of vasopressin and isoprenaline.

de Sousa R, Grosso A J Physiol. 1982; 329:281-96.

PMID: 6815322 PMC: 1224780. DOI: 10.1113/jphysiol.1982.sp014303.

High [K+] alters the stimulus-hydrosmotic response coupling in toad bladder.

Grosso A, de Sousa R Pflugers Arch. 1984; 400(4):349-55.

PMID: 6087265 DOI: 10.1007/BF00587531.

Forskolin mimics the hydrosmotic action of vasopressin in the urinary bladder of toads Bufo marinus.

de Sousa R, Grosso A J Physiol. 1985; 365:307-18.

PMID: 2993597 PMC: 1193004. DOI: 10.1113/jphysiol.1985.sp015774.

Amiloride inhibits the vasopressin-induced increase in epithelial water permeability.

Grosso A, Cragoe Jr E, DESOUSA R Pflugers Arch. 1990; 417(2):200-6.

PMID: 1964723 DOI: 10.1007/BF00370700.

References

Grosso A, Spinelli F, de Sousa R . Cytochalasin B and water transport. A scanning electron microscope study of the toad urinary bladder. Cell Tissue Res. 1978; 188(3):375-88. DOI: 10.1007/BF00219779. View

Taylor A, Mamelak M, REAVEN E, Maffly R . Vasopressin: possible role of microtubules and microfilaments in its action. Science. 1973; 181(4097):347-50. DOI: 10.1126/science.181.4097.347. View

KURIKI Y, RACKER E . Inhibition of (Na+, K+)adenosine triphosphatase and its partial reactions by quercetin. Biochemistry. 1976; 15(23):4951-6. DOI: 10.1021/bi00668a001. View

Bourguet J, Chevalier J, Hugon J . Alterations in membrane-associated particle distribution during antidiuretic challenge in frog urinary bladder epithelium. Biophys J. 1976; 16(6):627-39. PMC: 1334886. DOI: 10.1016/S0006-3495(76)85717-7. View

Ruphi M, de Sousa R, POSTERNAK J . Optical method for measuring water flow with automatic recording. Experientia. 1972; 28(11):1391-3. DOI: 10.1007/BF01965364. View

Schwartz A, Lindenmayer G, Allen J . The sodium-potassium adenosine triphosphatase: pharmacological, physiological and biochemical aspects. Pharmacol Rev. 1975; 27(01):3-134. View

Shoshan V, Campbell K, Maclennan D, Frodis W, Britt B . Quercetin inhibits Ca2+ uptake but not Ca2+ release by sarcoplasmic reticulum in skinned muscle fibers. Proc Natl Acad Sci U S A. 1980; 77(8):4435-8. PMC: 349858. DOI: 10.1073/pnas.77.8.4435. View

de Sousa R, Grosso A . Vasopressin-like effects of a hallucinogenic drug--harmaline--on sodium and water transport. J Membr Biol. 1978; 40(1):77-94. DOI: 10.1007/BF01909740. View

Singer I, Rotenberg D, Puschett J . Lithium-induced nephrogenic diabetes insipidus: in vivo and in vitro studies. J Clin Invest. 1972; 51(5):1081-91. PMC: 292237. DOI: 10.1172/JCI106900. View

10.

Grosso A, de Sousa R . Vasopressin-like effects of psychotropic drugs in amphibian epithelia. J Membr Biol. 1978; 40 Spec No:305-21. DOI: 10.1007/BF02026013. View

11.

Muller J, Kachadorian W, DiScala V . Evidence that ADH-stimulated intramembrane particle aggregates are transferred from cytoplasmic to luminal membranes in toad bladder epithelial cells. J Cell Biol. 1980; 85(1):83-95. PMC: 2110591. DOI: 10.1083/jcb.85.1.83. View

12.

Graziani Y, Chayoth R . Elevation of cyclic AMP level in Ehrlich ascites tumor cells by quercetin. Biochem Pharmacol. 1977; 26(13):1259-61. DOI: 10.1016/0006-2952(77)90116-2. View

13.

de Sousa R, Grosso A . Vanadate blocks cyclic AMP-induced stimulation of sodium and water transport in amphibian epithelia. Nature. 1979; 279(5716):803-4. DOI: 10.1038/279803a0. View

14.

Graziani Y, Winikoff J, Chayoth R . Regulation of cyclic AMP level and lactic acid production in Ehrlich ascites tumor cells. Biochim Biophys Acta. 1977; 497(2):499-506. DOI: 10.1016/0304-4165(77)90207-0. View