The Use of Heparin As a Simple Cost-effective Means of Controlling Background in Nucleic Acid Hybridization Procedures

Overview

Journal Nucleic Acids Res

Publisher Oxford University Press

Specialty Biochemistry

Date 1984 Jul 25

PMID 6087294

Citations 83

Authors

L Singh

K W Jones

Affiliations

Soon will be listed here.

Abstract

The use of heparin as a simple, effective and cheap substitute for conventional methods of controlling background in hybridization procedures is described and illustrated with reference to the use of DNA probes in filter and in situ hybridization. Possible specific mechanisms for this heparin effect are discussed.

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