Sharma A, Nair R, Achreja A, Mittal A, Gupta P, Balakrishnan K
Sci Adv. 2022; 8(39):eabq5575.
PMID: 36170375
PMC: 9519052.
DOI: 10.1126/sciadv.abq5575.
Mainali R, Zabalawi M, Long D, Buechler N, Quillen E, Key C
Elife. 2021; 10.
PMID: 33616039
PMC: 7901874.
DOI: 10.7554/eLife.64611.
Lai N, Fealy C, Kummitha C, Cabras S, Kirwan J, Hoppel C
Front Physiol. 2020; 11:677.
PMID: 32612543
PMC: 7308651.
DOI: 10.3389/fphys.2020.00677.
Sridharan S, Kurzawa N, Werner T, Gunthner I, Helm D, Huber W
Nat Commun. 2019; 10(1):1155.
PMID: 30858367
PMC: 6411743.
DOI: 10.1038/s41467-019-09107-y.
Shao X, Cao H, Zhao F, Peng M, Wang P, Li C
Mol Microbiol. 2019; 111(4):1057-1073.
PMID: 30677184
PMC: 6850173.
DOI: 10.1111/mmi.14211.
The regulation of neuronal mitochondrial metabolism by calcium.
Llorente-Folch I, Rueda C, Pardo B, Szabadkai G, Duchen M, Satrustegui J
J Physiol. 2015; 593(16):3447-62.
PMID: 25809592
PMC: 4560577.
DOI: 10.1113/JP270254.
A role for the mitochondrial pyruvate carrier as a repressor of the Warburg effect and colon cancer cell growth.
Schell J, Olson K, Jiang L, Hawkins A, Van Vranken J, Xie J
Mol Cell. 2014; 56(3):400-413.
PMID: 25458841
PMC: 4268416.
DOI: 10.1016/j.molcel.2014.09.026.
The pyruvate carboxylase-pyruvate dehydrogenase axis in islet pyruvate metabolism: Going round in circles?.
Sugden M, Holness M
Islets. 2011; 3(6):302-19.
PMID: 21934355
PMC: 3329512.
DOI: 10.4161/isl.3.6.17806.
Determining the in vivo regulation of cardiac pyruvate dehydrogenase based on label flux from hyperpolarised [1-13C]pyruvate.
Schroeder M, Atherton H, Heather L, Griffin J, Clarke K, Radda G
NMR Biomed. 2011; 24(8):980-987.
PMID: 21387444
PMC: 4604660.
DOI: 10.1002/nbm.1668.
Pivotal role of the C-terminal DW-motif in mediating inhibition of pyruvate dehydrogenase kinase 2 by dichloroacetate.
Li J, Kato M, Chuang D
J Biol Chem. 2009; 284(49):34458-67.
PMID: 19833728
PMC: 2797213.
DOI: 10.1074/jbc.M109.065557.
Monitoring phosphorylation of the pyruvate dehydrogenase complex.
Rardin M, Wiley S, Naviaux R, Murphy A, Dixon J
Anal Biochem. 2009; 389(2):157-64.
PMID: 19341700
PMC: 2713743.
DOI: 10.1016/j.ab.2009.03.040.
In vivo assessment of pyruvate dehydrogenase flux in the heart using hyperpolarized carbon-13 magnetic resonance.
Schroeder M, Cochlin L, Heather L, Clarke K, Radda G, Tyler D
Proc Natl Acad Sci U S A. 2008; 105(33):12051-6.
PMID: 18689683
PMC: 2515222.
DOI: 10.1073/pnas.0805953105.
Synthesis of amino acid cofactor in cysteine dioxygenase is regulated by substrate and represents a novel post-translational regulation of activity.
Dominy Jr J, Hwang J, Guo S, Hirschberger L, Zhang S, Stipanuk M
J Biol Chem. 2008; 283(18):12188-201.
PMID: 18308719
PMC: 2335356.
DOI: 10.1074/jbc.M800044200.
Distinct structural mechanisms for inhibition of pyruvate dehydrogenase kinase isoforms by AZD7545, dichloroacetate, and radicicol.
Kato M, Li J, Chuang J, Chuang D
Structure. 2007; 15(8):992-1004.
PMID: 17683942
PMC: 2871385.
DOI: 10.1016/j.str.2007.07.001.
Metabolic inertia in contracting skeletal muscle: a novel approach for pharmacological intervention in peripheral vascular disease.
Greenhaff P, Campbell-OSullivan S, Constantin-Teodosiu D, Poucher S, Roberts P, Timmons J
Br J Clin Pharmacol. 2004; 57(3):237-43.
PMID: 14998419
PMC: 1884458.
DOI: 10.1046/j.1365-2125.2003.01989.x.
The acetyl group deficit at the onset of contraction in ischaemic canine skeletal muscle.
Roberts P, Loxham S, Poucher S, Constantin-Teodosiu D, Greenhaff P
J Physiol. 2002; 544(2):591-602.
PMID: 12381829
PMC: 2290584.
DOI: 10.1113/jphysiol.2002.021097.
Monovalent Cation Activation of Plant Pyruvate Dehydrogenase Kinase.
Schuller K, Gemel J, Randall D
Plant Physiol. 1993; 102(1):139-143.
PMID: 12231804
PMC: 158756.
DOI: 10.1104/pp.102.1.139.
An essential role of Glu-243 and His-239 in the phosphotransfer reaction catalyzed by pyruvate dehydrogenase kinase.
Tuganova A, Yoder M, Popov K
J Biol Chem. 2001; 276(21):17994-9.
PMID: 11278487
PMC: 2144735.
DOI: 10.1074/jbc.M009327200.
Mode of action of liver tumor induction by trichloroethylene and its metabolites, trichloroacetate and dichloroacetate.
Bull R
Environ Health Perspect. 2000; 108 Suppl 2:241-59.
PMID: 10807555
PMC: 1637759.
DOI: 10.1289/ehp.00108s2241.
Fibre-type specific modification of the activity and regulation of skeletal muscle pyruvate dehydrogenase kinase (PDK) by prolonged starvation and refeeding is associated with targeted regulation of PDK isoenzyme 4 expression.
Sugden M, Kraus A, Harris R, Holness M
Biochem J. 2000; 346 Pt 3:651-7.
PMID: 10698691
PMC: 1220897.