» Articles » PMID: 4395746

Cardio-selective Beta-adrenoceptor Blockade and the Coronary Circulation

Overview
Journal Br J Pharmacol
Publisher Wiley
Specialty Pharmacology
Date 1970 Nov 1
PMID 4395746
Citations 11
Authors
Affiliations
Soon will be listed here.
Abstract

After blockade of myocardial, but not coronary vascular beta-adrenoceptors by practolol, cardiac sympathetic stimulation or exogenously administered noradrenaline gave rise to coronary vasoconstriction, possibly due to stimulation of coronary alpha-adrenoceptors.

Citing Articles

The role of adenosine in functional hyperaemia in the coronary circulation of anaesthetized dogs.

Karim F, Goonewardene I J Physiol. 1996; 490 ( Pt 3):793-803.

PMID: 8683477 PMC: 1158716. DOI: 10.1113/jphysiol.1996.sp021187.


Regulation of large coronary vessels by adrenergic mechanisms in conscious dogs.

Vatner S, Macho P Basic Res Cardiol. 1981; 76(5):508-17.

PMID: 6272684 DOI: 10.1007/BF01908352.


Catecholamine-induced vasodilator metabolite release from guinea-pig hearts is not due to increased myocardial activity.

Broadley K, Rothaul A Pflugers Arch. 1981; 391(2):147-53.

PMID: 6270628 DOI: 10.1007/BF00657006.


The evidence for alpha-adrenoceptors in the coronary circulation and their possible relevance to the physiological regulation of myocardial blood flow.

Parratt J Basic Res Cardiol. 1981; 76(5):485-93.

PMID: 6118126 DOI: 10.1007/BF01908348.


Characterization of the coronary vascular -adrenoceptor in the pig.

Drew G, Levy G Br J Pharmacol. 1972; 46(2):348-50.

PMID: 4405612 PMC: 1666354. DOI: 10.1111/j.1476-5381.1972.tb06880.x.


References
1.
FEIGL E . Sympathetic control of coronary circulation. Circ Res. 1967; 20(2):262-71. DOI: 10.1161/01.res.20.2.262. View

2.
GAAL P, Kattus A, Kolin A, Ross G . Effects of adrenaline and noradrenaline on coronary blood flow before and after beta-adrenergic blockade. Br J Pharmacol Chemother. 1966; 26(3):713-22. PMC: 1510700. DOI: 10.1111/j.1476-5381.1966.tb01851.x. View

3.
Dunlop D, Shanks R . Selective blockade of adrenoceptive beta receptors in the heart. Br J Pharmacol Chemother. 1968; 32(1):201-18. PMC: 1570292. DOI: 10.1111/j.1476-5381.1968.tb00444.x. View

4.
Ross G, Jorgensen C . Effects of a cardio-selective beta-adrenergic blocking agent on the heart and coronary circulation. Cardiovasc Res. 1970; 4(2):148-53. DOI: 10.1093/cvr/4.2.148. View

5.
Parratt J, Wadsworth R . The effect of "selective" beta-adrenoceptor blocking drugs on the myocardial circulation. Br J Pharmacol. 1970; 39(2):296-308. PMC: 1702852. DOI: 10.1111/j.1476-5381.1970.tb12893.x. View