Copper Drives Remodeling of Metabolic State and Progression of Clear Cell Renal Cell Carcinoma

Overview

Journal Cancer Discov

Specialty Oncology

Date 2024 Oct 30

PMID 39476412

Authors

Megan E Bischoff

Behrouz Shamsaei

Juechen Yang

Dina Secic

Bhargav Vemuri

Julie A Reisz

Angelo DAlessandro

Caterina Bartolacci

Rafal Adamczak

Lucas Schmidt

Jiang Wang

Amelia Martines

Jahnavi Venkat

Vanina Toffessi Tcheuyap

Jacek Biesiada

Catherine A Behrmann

Katherine E Vest

James Brugarolas

Pier Paolo Scaglioni

David R Plas

Krushna C Patra

Shuchi Gulati

Julio A Landero Figueroa

Jarek Meller

John T Cunningham

Maria F Czyzyk-Krzeska

Affiliations

Soon will be listed here.

Abstract

The work establishes a requirement for glucose-dependent coordination between energy production and redox homeostasis, which is fundamental for the survival of cancer cells that accumulate Cu and contributes to tumor growth.

Citing Articles

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PMID: 39719623 PMC: 11669227. DOI: 10.1186/s13008-024-00140-y.

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