Thrombocytosis and Megakaryocyte Changes Associated with PRCA

Overview

Journal Blood Adv

Specialty Hematology

Date 2024 Apr 2

PMID 38564765

Authors

Joelle Abdallah

Robert George Williams

Hussein Awada

Ganesh Raman

Yusuf Ozcan

Mark Orland

Mutlu Mete

Weina Chen

Carmelo Gurnari

Jaroslaw P Maciejewski

Taha Bat

Affiliations

Soon will be listed here.

References

Socolovsky M, Lodish H, Daley G . Control of hematopoietic differentiation: lack of specificity in signaling by cytokine receptors. Proc Natl Acad Sci U S A. 1998; 95(12):6573-5. PMC: 33861. DOI: 10.1073/pnas.95.12.6573. View

Jimenez K, Leitner F, Leitner A, Scharbert G, Schwabl P, Kramer A . Iron deficiency-induced thrombocytosis increases thrombotic tendency in rats. Haematologica. 2020; 106(3):782-794. PMC: 7928018. DOI: 10.3324/haematol.2019.245092. View

Sawada K, Fujishima N, Hirokawa M . Acquired pure red cell aplasia: updated review of treatment. Br J Haematol. 2008; 142(4):505-14. PMC: 2592349. DOI: 10.1111/j.1365-2141.2008.07216.x. View

Gurnari C, Maciejewski J . How I manage acquired pure red cell aplasia in adults. Blood. 2021; 137(15):2001-2009. PMC: 8057257. DOI: 10.1182/blood.2021010898. View

Hacein-Bey-Abina S, Estienne M, Bessoles S, Echchakir H, Pederzoli-Ribeil M, Chiron A . Erythropoietin is a major regulator of thrombopoiesis in thrombopoietin-dependent and -independent contexts. Exp Hematol. 2020; 88:15-27. DOI: 10.1016/j.exphem.2020.07.006. View

Hattangadi S, Wong P, Zhang L, Flygare J, Lodish H . From stem cell to red cell: regulation of erythropoiesis at multiple levels by multiple proteins, RNAs, and chromatin modifications. Blood. 2011; 118(24):6258-68. PMC: 3236116. DOI: 10.1182/blood-2011-07-356006. View

Xavier-Ferrucio J, Scanlon V, Li X, Zhang P, Lozovatsky L, Ayala-Lopez N . Low iron promotes megakaryocytic commitment of megakaryocytic-erythroid progenitors in humans and mice. Blood. 2019; 134(18):1547-1557. PMC: 6839952. DOI: 10.1182/blood.2019002039. View

Pronk C, Rossi D, Mansson R, Attema J, Norddahl G, Chan C . Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy. Cell Stem Cell. 2008; 1(4):428-42. DOI: 10.1016/j.stem.2007.07.005. View

Xavier R, Devaraj S, Sadasivam V, Prakasam O, Menon N, Hariharan A . Thymoma associated with pure red cell aplasia: a case report and literature review. Indian J Thorac Cardiovasc Surg. 2020; 36(4):404-408. PMC: 7525650. DOI: 10.1007/s12055-019-00875-2. View

10.

BURSTEIN S . Cytokines, platelet production and hemostasis. Platelets. 2010; 8(2-3):93-104. DOI: 10.1080/09537109709169324. View

11.

Lee N, Patel B, Etra A, Bat T, Ibrahim I, Vusirikala M . SARS-CoV-2 infection associated with aplastic anemia and pure red cell aplasia. Blood Adv. 2022; 6(13):3840-3843. PMC: 9040401. DOI: 10.1182/bloodadvances.2022007174. View

12.

Ulirsch J, Verboon J, Kazerounian S, Guo M, Yuan D, Ludwig L . The Genetic Landscape of Diamond-Blackfan Anemia. Am J Hum Genet. 2018; 103(6):930-947. PMC: 6288280. DOI: 10.1016/j.ajhg.2018.10.027. View

13.

Stohlawetz P, Dzirlo L, Hergovich N, Lackner E, Mensik C, Eichler H . Effects of erythropoietin on platelet reactivity and thrombopoiesis in humans. Blood. 2000; 95(9):2983-9. View

14.

Cheng E, Luo Q, Bruscia E, Renda M, Troy J, Massaro S . Role for MKL1 in megakaryocytic maturation. Blood. 2009; 113(12):2826-34. PMC: 2661865. DOI: 10.1182/blood-2008-09-180596. View

15.

Means Jr R . Pure red cell aplasia. Blood. 2016; 128(21):2504-2509. DOI: 10.1182/blood-2016-05-717140. View

16.

Kaupke C, Butler G, Vaziri N . Effect of recombinant human erythropoietin on platelet production in dialysis patients. J Am Soc Nephrol. 1993; 3(10):1672-9. DOI: 10.1681/ASN.V3101672. View

17.

Broudy V, Lin N, Kaushansky K . Thrombopoietin (c-mpl ligand) acts synergistically with erythropoietin, stem cell factor, and interleukin-11 to enhance murine megakaryocyte colony growth and increases megakaryocyte ploidy in vitro. Blood. 1995; 85(7):1719-26. View

18.

Homoncik M, Jilma-Stohlawetz P, Schmid M, Ferlitsch A, Peck-Radosavljevic M . Erythropoietin increases platelet reactivity and platelet counts in patients with alcoholic liver cirrhosis: a randomized, double-blind, placebo-controlled study. Aliment Pharmacol Ther. 2004; 20(4):437-43. DOI: 10.1111/j.1365-2036.2004.02088.x. View

19.

Heinisch B, Vcelar B, Kapiotis S, Blann A, Wolzt M, Siller-Matula J . The effect of erythropoietin on platelet and endothelial activation markers: a prospective trial in healthy volunteers. Platelets. 2011; 23(5):352-8. DOI: 10.3109/09537104.2011.631621. View

20.

Lodish H, Flygare J, Chou S . From stem cell to erythroblast: regulation of red cell production at multiple levels by multiple hormones. IUBMB Life. 2010; 62(7):492-6. PMC: 2893266. DOI: 10.1002/iub.322. View