Dissecting the Immune System through Gene Regulation
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The immune system plays a dual role in human health, functioning both as a protector against pathogens and, at times, as a contributor to disease. This feature emphasizes the importance to uncover the underlying causes of its malfunctions, necessitating an in-depth analysis in both pathological and physiological conditions to better understand the immune system and immune disorders. Recent advances in scientific technology have enabled extensive investigations into gene regulation, a crucial mechanism governing cellular functionality. Studying gene regulatory mechanisms within the immune system is a promising avenue for enhancing our understanding of immune cells and the immune system as a whole. The gene regulatory mechanisms, revealed through various methodologies, and their implications in the field of immunology are discussed in this chapter.
Emerging Mechanisms and Biomarkers Associated with T-Cells and B-Cells in Autoimmune Disorders.
Sivalingam A Clin Rev Allergy Immunol. 2025; 68(1):14.
PMID: 39932617 DOI: 10.1007/s12016-025-09022-9.