The Effect of In vitro Digestion on the Interaction Between Polysaccharides Derived from and Intestinal Mucus

Overview

Journal Food Sci Nutr

Specialty Biotechnology

Date 2024 Feb 19

PMID 38370047

Authors

Sai Ma

Xinyi Li

Qi Tao

Qiuhui Hu

Wenjian Yang

Benard Muinde Kimatu

Gaoxing Ma

Affiliations

Soon will be listed here.

Abstract

polysaccharides (PEPs) have been proven to display multiple activities through digestive system action, from which the digestion products should first interact with intestinal mucus (MUC), followed by the function of intestinal cells. Hence, possible interacting characterizations between MUC and in vitro simulated digestion products of polysaccharides (DPEPs) and PEP were carried out in the present study. Results showed that both PEP and DPEP could significantly interact with MUC. Moreover, digestion can modify the interaction between polysaccharides and MUC; the degree of interaction also changes with time incrementing. Viscosity could be decreased after digesting. According to the zeta potential and stability analysis result, the digestive behavior could be regular and stable between polysaccharides and MUC interactions. Following fluorescence and infrared spectra, the structure of polysaccharides and mucin might be changed by digestion between polysaccharides and MUC. The study indicates that the interaction formed between DPEP and MUC might indirectly impact the exercise and immune activities of polysaccharides and influence the transportation of other nutrients. Overall, our results, the absorption and transport pathways of PEP, can be initially revealed and may provide a novel research viewpoint on the active mechanism of PEP in the intestinal tract.

Citing Articles

The effect of in vitro digestion on the interaction between polysaccharides derived from and intestinal mucus.

Ma S, Li X, Tao Q, Hu Q, Yang W, Kimatu B Food Sci Nutr. 2024; 12(2):1318-1329.

PMID: 38370047 PMC: 10867464. DOI: 10.1002/fsn3.3845.

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