From Ocean to Medicine: Harnessing Seaweed's Potential for Drug Development
Overview
Chemistry
Molecular Biology
Affiliations
Seaweed, a miscellaneous group of marine algae, has long been recognized for its rich nutritional composition and bioactive compounds, being considered nutraceutical ingredient. This revision delves into the promising role of seaweed-derived nutrients as a beneficial resource for drug discovery and innovative product development. Seaweeds are abundant sources of essential vitamins, minerals, polysaccharides, polyphenols, and unique secondary metabolites, which reveal a wide range of biological activities. These bioactive compounds possess potential therapeutic properties, making them intriguing candidates for drug leads in various medical applications and pharmaceutical drug development. It explores their pharmacological properties, including antioxidant, anti-inflammatory, antimicrobial, and anticancer activities, shedding light on their potential as therapeutic agents. Moreover, the manuscript provides insights into the development of formulation strategies and delivery systems to enhance the bioavailability and stability of seaweed-derived compounds. The manuscript also discusses the challenges and opportunities associated with the integration of seaweed-based nutrients into the pharmaceutical and nutraceutical industries. Regulatory considerations, sustainability, and scalability of sustainable seaweed sourcing and cultivation methods are addressed, emphasizing the need for a holistic approach in harnessing seaweed's potential. This revision underscores the immense potential of seaweed-derived compounds as a valuable reservoir for drug leads and product development. By bridging the gap between marine biology, pharmacology, and product formulation, this research contributes to the critical advancement of sustainable and innovative solutions in the pharmaceutical and nutraceutical sectors.
Zeb L, Gerhardt A, Johannesen B, Underhaug J, Jordheim M ACS Sustain Chem Eng. 2024; 12(40):14921-14929.
PMID: 39391092 PMC: 11462601. DOI: 10.1021/acssuschemeng.4c06736.
Molecular Docking of Seaweed-Derived Drug Fucoxanthin Against the Monkeypox Virus.
Nikitha R, Afeeza K, Suresh V, Dilipan E Cureus. 2024; 16(4):e58730.
PMID: 38779278 PMC: 11110489. DOI: 10.7759/cureus.58730.
Seaweed Proteins: A Step towards Sustainability?.
Pereira L, Cotas J, Goncalves A Nutrients. 2024; 16(8).
PMID: 38674814 PMC: 11054349. DOI: 10.3390/nu16081123.
Seaweeds as Nutraceutical Elements and Drugs for Diabetes Mellitus: Future Perspectives.
Cotas J, Lomartire S, Pereira L, Valado A, Marques J, Goncalves A Mar Drugs. 2024; 22(4).
PMID: 38667785 PMC: 11051413. DOI: 10.3390/md22040168.
What is the role of microbial biotechnology and genetic engineering in medicine?.
Santos-Beneit F Microbiologyopen. 2024; 13(2):e1406.
PMID: 38556942 PMC: 10982607. DOI: 10.1002/mbo3.1406.