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Questions-a Research Agenda for the Future

Abstract

The genus of parasitic nematodes have a fascinating life cycle and biology, but are also important pathogens of people and a World Health Organization-defined neglected tropical disease. Here, a community of researchers have posed thirteen major questions about biology and infection that sets a research agenda for the future. This article is part of the Theo Murphy meeting issue ': omics to worm-free populations'.

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References
1.
Thamsborg S, Ketzis J, Horii Y, Matthews J . Strongyloides spp. infections of veterinary importance. Parasitology. 2016; 144(3):274-284. DOI: 10.1017/S0031182016001116. View

2.
Hotez P, Hawdon J, Schad G . Hookworm larval infectivity, arrest and amphiparatenesis: the Caenorhabditis elegans Daf-c paradigm. Parasitol Today. 1993; 9(1):23-6. DOI: 10.1016/0169-4758(93)90159-d. View

3.
Tindall N, Wilson P . A basis to extend the proof of migration routes of immature parasites inside hosts: estimated time of arrival of Nippostrongylus brasiliensis and Strongyloides ratti in the gut of the rat. Parasitology. 1990; 100 Pt 2:275-80. DOI: 10.1017/s0031182000061278. View

4.
Stoltzfus J, Bart S, Lok J . cGMP and NHR signaling co-regulate expression of insulin-like peptides and developmental activation of infective larvae in Strongyloides stercoralis. PLoS Pathog. 2014; 10(7):e1004235. PMC: 4092141. DOI: 10.1371/journal.ppat.1004235. View

5.
Ko P, Haraguchi M, Hara T, Hieu D, Ito A, Tanaka R . Population genetics study of Strongyloides fuelleborni and phylogenetic considerations on primate-infecting species of Strongyloides based on their mitochondrial genome sequences. Parasitol Int. 2022; 92:102663. DOI: 10.1016/j.parint.2022.102663. View