Manipulating the Destiny of Wild Populations Using CRISPR
Overview
Affiliations
Genetic biocontrol aims to suppress or modify populations of species to protect public health, agriculture, and biodiversity. Advancements in genome engineering technologies have fueled a surge in research in this field, with one gene editing technology, CRISPR, leading the charge. This review focuses on the current state of CRISPR technologies for genetic biocontrol of pests and highlights the progress and ongoing challenges of using these approaches.
Engineering drive-selection balance for localized population suppression with neutral dynamics.
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PMID: 39903106 PMC: 11831207. DOI: 10.1073/pnas.2414207122.
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PMID: 39336621 PMC: 11432399. DOI: 10.3390/insects15090653.
Altering traits and fates of wild populations with Mendelian DNA sequence modifying Allele Sails.
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PMID: 39138152 PMC: 11322531. DOI: 10.1038/s41467-024-50992-9.
Eliminating malaria vectors with precision-guided sterile males.
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PMID: 38917000 PMC: 11228498. DOI: 10.1073/pnas.2312456121.