An Enhancer Within Abcb11 Regulates G6pc2 in C57BL/6 Mouse Pancreatic Islets
Overview
Overview
Authors
Authors
Affiliations
Affiliations
Soon will be listed here.
Abstract
Article Highlights:
Citing Articles
Martin C, Oeser J, Wangmo T, Flemming B, Attie A, Keller M J Mol Endocrinol. 2024; 73(3).
PMID: 39121091 PMC: 11439184. DOI: 10.1530/JME-24-0051.
References
1.
OBrien R
. Moving on from GWAS: functional studies on the G6PC2 gene implicated in the regulation of fasting blood glucose. Curr Diab Rep. 2013; 13(6):768-77.
PMC: 4041587.
DOI: 10.1007/s11892-013-0422-8.
View
2.
Chen W, Erdos M, Jackson A, Saxena R, Sanna S, Silver K
. Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels. J Clin Invest. 2008; 118(7):2620-8.
PMC: 2398737.
DOI: 10.1172/JCI34566.
View
3.
Miguel-Escalada I, Bonas-Guarch S, Cebola I, Ponsa-Cobas J, Mendieta-Esteban J, Atla G
. Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes. Nat Genet. 2019; 51(7):1137-1148.
PMC: 6640048.
DOI: 10.1038/s41588-019-0457-0.
View
4.
Mitok K, Freiberger E, Schueler K, Rabaglia M, Stapleton D, Kwiecien N
. Islet proteomics reveals genetic variation in dopamine production resulting in altered insulin secretion. J Biol Chem. 2018; 293(16):5860-5877.
PMC: 5912463.
DOI: 10.1074/jbc.RA117.001102.
View
5.
Pasquali L, Gaulton K, Rodriguez-Segui S, Mularoni L, Miguel-Escalada I, Akerman I
. Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants. Nat Genet. 2014; 46(2):136-143.
PMC: 3935450.
DOI: 10.1038/ng.2870.
View