Historic Recurrences in Medicinal Chemistry: Nature-inspired Structures As a New Opportunity for Novel Multi-target Anti-Alzheimer's Drugs

Overview

Journal Neural Regen Res

Date 2023 Jul 14

PMID 37449616

Authors

Luca Piemontese

Affiliations

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References

Piemontese L, Sergio R, Rinaldo F, Brunetti L, Perna F, Santos M . Deep Eutectic Solvents as Effective Reaction Media for the Synthesis of 2-Hydroxyphenylbenzimidazole-based Scaffolds en Route to Donepezil-Like Compounds. Molecules. 2020; 25(3). PMC: 7037276. DOI: 10.3390/molecules25030574. View

Leuci R, Brunetti L, Laghezza A, Piemontese L, Carrieri A, Pisani L . A New Series of Aryloxyacetic Acids Endowed with Multi-Target Activity towards Peroxisome Proliferator-Activated Receptors (PPARs), Fatty Acid Amide Hydrolase (FAAH), and Acetylcholinesterase (AChE). Molecules. 2022; 27(3). PMC: 8839882. DOI: 10.3390/molecules27030958. View

Brunetti L, Leuci R, Carrieri A, Catto M, Occhineri S, Vinci G . Structure-based design of novel donepezil-like hybrids for a multi-target approach to the therapy of Alzheimer's disease. Eur J Med Chem. 2022; 237:114358. DOI: 10.1016/j.ejmech.2022.114358. View

Piemontese L, Vitucci G, Catto M, Laghezza A, Perna F, Rullo M . Natural Scaffolds with Multi-Target Activity for the Potential Treatment of Alzheimer's Disease. Molecules. 2018; 23(9). PMC: 6225478. DOI: 10.3390/molecules23092182. View

Piemontese L, Brunetti L, Leuci R . Can foods influence the onset and progress of neurodegenerative diseases?. Neural Regen Res. 2022; 17(11):2443-2444. PMC: 9120676. DOI: 10.4103/1673-5374.335810. View

Ji C, Fan Y, Zhao L . Review on biological degradation of mycotoxins. Anim Nutr. 2018; 2(3):127-133. PMC: 5941024. DOI: 10.1016/j.aninu.2016.07.003. View

Carocci A, Barbarossa A, Leuci R, Carrieri A, Brunetti L, Laghezza A . Novel Phenothiazine/Donepezil-like Hybrids Endowed with Antioxidant Activity for a Multi-Target Approach to the Therapy of Alzheimer's Disease. Antioxidants (Basel). 2022; 11(9). PMC: 9495854. DOI: 10.3390/antiox11091631. View

Cervini C, Gallo A, Piemontese L, Magista D, Logrieco A, Ferrara M . Effects of temperature and water activity change on ecophysiology of ochratoxigenic Aspergillus carbonarius in field-simulating conditions. Int J Food Microbiol. 2019; 315:108420. DOI: 10.1016/j.ijfoodmicro.2019.108420. View

Brunetti L, Laghezza A, Loiodice F, Tortorella P, Piemontese L . Combining fatty acid amide hydrolase (FAAH) inhibition with peroxisome proliferator-activated receptor (PPAR) activation: a new potential multi-target therapeutic strategy for the treatment of Alzheimer's disease. Neural Regen Res. 2019; 15(1):67-68. PMC: 6862411. DOI: 10.4103/1673-5374.264458. View

10.

Poliseno V, Chaves S, Brunetti L, Loiodice F, Carrieri A, Laghezza A . Derivatives of Tenuazonic Acid as Potential New Multi-Target Anti-Alzheimer's Disease Agents. Biomolecules. 2021; 11(1). PMC: 7830597. DOI: 10.3390/biom11010111. View

11.

Brunetti L, Leuci R, Colonna M, Carrieri R, Celentano F, Bozzo G . Food Industry Byproducts as Starting Material for Innovative, Green Feed Formulation: A Sustainable Alternative for Poultry Feeding. Molecules. 2022; 27(15). PMC: 9332232. DOI: 10.3390/molecules27154735. View

12.

De Deurwaerdere P, Chagraoui A, Di Giovanni G . Serotonin/dopamine interaction: Electrophysiological and neurochemical evidence. Prog Brain Res. 2021; 261:161-264. DOI: 10.1016/bs.pbr.2021.02.001. View

13.

Leuci R, Brunetti L, Poliseno V, Laghezza A, Loiodice F, Tortorella P . Natural Compounds for the Prevention and Treatment of Cardiovascular and Neurodegenerative Diseases. Foods. 2020; 10(1). PMC: 7824130. DOI: 10.3390/foods10010029. View

14.

Piemontese L . An innovative approach for the treatment of Alzheimer's disease: the role of peroxisome proliferator-activated receptors and their ligands in development of alternative therapeutic interventions. Neural Regen Res. 2018; 14(1):43-45. PMC: 6262998. DOI: 10.4103/1673-5374.241043. View