Prediction of Linear B Cell Epitopes in Proteins

Overview

Journal Methods Mol Biol

Specialty Molecular Biology

Date 2023 May 31

PMID 37258915

Authors

Juan R de Los Toyos

Affiliations

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Abstract

The accurate prediction of B cell epitopes is crucial for the design and development of vaccines, especially of those preventive for emerging pathogenic diseases. Preventive vaccines are mainly based on the induction of highly specific neutralizing antibodies. This chapter deals with some prediction methods, which are currently available as user-friendly online servers, to predict B cell epitopes in proteins. A final assessment to validate these predictions is done by recurring to the Immune Epitope Database (IEDB).

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