» Articles » PMID: 37101538

Comparison of Surface Dose During Whole Breast Radiation Therapy on Halcyon and TrueBeam Using Cherenkov Imaging

Overview
Date 2023 Apr 27
PMID 37101538
Authors
Affiliations
Soon will be listed here.
Abstract

The emergence of the Halcyon linear accelerator has allowed for increased patient throughput and improved treatment times for common treatment sites in radiation oncology. However, it has been shown that this can lead to increased surface dose in sites like breast cancer compared with treatments on conventional machines with flattened radiation beams. Cherenkov imaging can be used to estimate surface dose by detection of Cherenkov photons emitted in proportion to energy deposition from high energy electrons in tissue. Phantom studies were performed with both square beams in reference conditions and with clinical treatments, and dosimeter readings and Cherenkov images report higher surface dose (25% for flat phantom entrance dose, 5.9% for breast phantom treatment) from Halcyon beam deliveries than for equivalent deliveries from a TrueBeam linac. Additionally, the first Cherenkov images of a patient treated with Halcyon were acquired, and superficial dose was estimated.

Citing Articles

Characterization of Cherenkov imaging parameters and positional constraints on an O-ring linear accelerator.

Alexander D, Majji S, Jermyn M, Byrd B, Bruza P, Li T Phys Med Biol. 2023; 68(20).

PMID: 37757840 PMC: 10693929. DOI: 10.1088/1361-6560/acfdf2.

References
1.
Mesbahi A . Dosimetric characteristics of unflattened 6 MV photon beams of a clinical linear accelerator: a Monte Carlo study. Appl Radiat Isot. 2007; 65(9):1029-36. DOI: 10.1016/j.apradiso.2007.04.023. View

2.
Zhuang A, Olch A . Validation of OSLD and a treatment planning system for surface dose determination in IMRT treatments. Med Phys. 2014; 41(8):081720. DOI: 10.1118/1.4890795. View

3.
Constantin M, Perl J, LoSasso T, Salop A, Whittum D, Narula A . Modeling the truebeam linac using a CAD to Geant4 geometry implementation: dose and IAEA-compliant phase space calculations. Med Phys. 2011; 38(7):4018-24. DOI: 10.1118/1.3598439. View

4.
Decker S, Alexander D, Hachadorian R, Zhang R, Gladstone D, Bruza P . Estimation of diffuse Cherenkov optical emission from external beam radiation build-up in tissue. J Biomed Opt. 2021; 26(9). PMC: 8451315. DOI: 10.1117/1.JBO.26.9.098003. View

5.
Hachadorian R, Bruza P, Jermyn M, Mazhar A, Cuccia D, Jarvis L . Correcting Cherenkov light attenuation in tissue using spatial frequency domain imaging for quantitative surface dosimetry during whole breast radiation therapy. J Biomed Opt. 2018; 24(7):1-10. PMC: 6228320. DOI: 10.1117/1.JBO.24.7.071609. View