Preparation of Hydrogel Composites Using a Sustainable Approach for In Situ Silver Nanoparticles Formation

Overview

Journal Materials (Basel)

Publisher MDPI

Date 2023 Mar 29

PMID 36984014

Authors

Laura Chronopoulou

Roya Binaymotlagh

Sara Cerra

Farid Hajareh Haghighi

Enea Gino Di Domenico

Francesca Sivori

Ilaria Fratoddi

Silvano Mignardi

Cleofe Palocci

Affiliations

Soon will be listed here.

Abstract

The recognized antibacterial properties of silver nanoparticles (AgNPs) characterize them as attractive nanomaterials for developing new bioactive materials less prone to the development of antibiotic resistance. In this work, we developed new composites based on self-assembling Fmoc-Phe3 peptide hydrogels impregnated with in situ prepared AgNPs. Different methodologies, from traditional to innovative and eco-sustainable, were compared. The obtained composites were characterized from a hydrodynamic, structural, and morphological point of view, using different techniques such as DLS, SEM, and rheological measurements to evaluate how the choice of the reducing agent determines the characteristics of AgNPs and how their presence within the hydrogel affects their structure and properties. Moreover, the antibacterial properties of these composites were tested against , a major human pathogen responsible for a wide range of clinical infections. Results demonstrated that the hydrogel composites containing AgNPs (hgel@AgNPs) could represent promising biomaterials for treating -related infections.

Citing Articles

Preparation of Peptide-Based Magnetogels for Removing Organic Dyes from Water.

Hajareh Haghighi F, Binaymotlagh R, Pintilei P, Chronopoulou L, Palocci C Gels. 2024; 10(5).

PMID: 38786204 PMC: 11120949. DOI: 10.3390/gels10050287.

Liposome-Hydrogel Composites for Controlled Drug Delivery Applications.

Binaymotlagh R, Hajareh Haghighi F, Chronopoulou L, Palocci C Gels. 2024; 10(4).

PMID: 38667703 PMC: 11048854. DOI: 10.3390/gels10040284.

Peptide-Hydrogel Nanocomposites for Anti-Cancer Drug Delivery.

Hajareh Haghighi F, Binaymotlagh R, Fratoddi I, Chronopoulou L, Palocci C Gels. 2023; 9(12).

PMID: 38131939 PMC: 10742474. DOI: 10.3390/gels9120953.

Biosynthesis of Peptide Hydrogel-Titania Nanoparticle Composites with Antibacterial Properties.

Binaymotlagh R, Hajareh Haghighi F, Di Domenico E, Sivori F, Truglio M, Del Giudice A Gels. 2023; 9(12).

PMID: 38131926 PMC: 10742879. DOI: 10.3390/gels9120940.

Editorial: New Advances in Nanomaterials.

Wang C, Yu X, Liu M, Deng Z, Zhang D, Zhang H Materials (Basel). 2023; 16(9).

PMID: 37176417 PMC: 10180016. DOI: 10.3390/ma16093535.

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