Circulating Cervical Cancer Biomarkers Potentially Useful in Medical Attention (Review)

Overview

Journal Mol Clin Oncol

Specialty Oncology

Date 2023 Feb 10

PMID 36761385

Authors

Ruth Ruiz Esparza Garrido

Mercedes Gutierrez

Miguel Angel Velazquez Flores

Affiliations

Soon will be listed here.

Abstract

Cervical cancer (CC) is a public health problem worldwide, including Mexico. This type of cancer is the fourth most frequent in women worldwide; in Mexico it is the second most common type in women after breast cancer. The diagnosis of CC is based mainly on Pap smears and colposcopy and the identification of molecular tools that serve as a support for these methods is urgent. Regarding this, differential expressions of specific circulating biomolecules has been detected and, based on this, they have been postulated as potential biomarkers for CC diagnosis, prognosis, and/or to identify the response to treatments. Importantly, the combined analysis of these molecules considerably improves their efficacy as biomarkers and their potential use in the medical attention is promising.

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