Error-corrected Next-generation Sequencing to Advance Nonclinical Genotoxicity and Carcinogenicity Testing

Overview

Journal Nat Rev Drug Discov

Specialty Pharmacology

Date 2023 Jan 16

PMID 36646809

Authors

Francesco Marchetti

Renato Cardoso

Connie L Chen

George R Douglas

Joanne Elloway

Patricia A Escobar

Tod Harper Jr

Robert H Heflich

Darren Kidd

Anthony M Lynch

Meagan B Myers

Barbara L Parsons

Jesse J Salk

Raja S Settivari

Stephanie L Smith-Roe

Kristine L Witt

Carole Yauk

Robert R Young

Shaofei Zhang

Sheroy Minocherhomji

Affiliations

Soon will be listed here.

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Evaluating the mutagenicity of N-nitrosodimethylamine in 2D and 3D HepaRG cell cultures using error-corrected next generation sequencing.

Seo J, Le Y, Revollo J, Miranda-Colon J, Xu H, McKinzie P Arch Toxicol. 2024; 98(6):1919-1935.

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Genome-wide direct quantification of in vivo mutagenesis using high-accuracy paired-end and complementary consensus sequencing.

You X, Cao Y, Suzuki T, Shao J, Zhu B, Masumura K Nucleic Acids Res. 2023; 51(21):e109.

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References

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