Stephanie L Smith-Roe
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Explore the profile of Stephanie L Smith-Roe including associated specialties, affiliations and a list of published articles.
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33
Citations
479
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Recent Articles
1.
Witt K, van Benthem J, Kobets T, Chen G, Kelber O, Krzykwa J, et al.
Food Chem Toxicol
. 2025 Jan;
197:115277.
PMID: 39855614
Botanicals have long been used to promote health and treat diseases, but the safety of many currently marketed botanicals has not been adequately evaluated. Given the chemical complexity of botanicals,...
2.
Schuster D, LeBlanc D, Zhou G, Meier M, Dodge A, White P, et al.
Environ Sci Technol
. 2024 Nov;
58(49):21450-21463.
PMID: 39602390
Polycyclic aromatic hydrocarbons (PAHs) are common environmental pollutants that originate from the incomplete combustion of organic materials. We investigated the clastogenicity and mutagenicity of benzo[]fluoranthene (BbF), one of 16 priority...
3.
Smith-Roe S, Hobbs C, Hull V, Auman J, Recio L, Streicker M, et al.
Mutat Res Genet Toxicol Environ Mutagen
. 2023 Sep;
891:503669.
PMID: 37770135
Duplex sequencing (DS) is an error-corrected next-generation sequencing method in which molecular barcodes informatically link PCR-copies back to their source DNA strands, enabling computational removal of errors in consensus sequences....
4.
Marchetti F, Cardoso R, Chen C, Douglas G, Elloway J, Escobar P, et al.
Mutat Res Rev Mutat Res
. 2023 Aug;
792:108466.
PMID: 37643677
Error-corrected Next Generation Sequencing (ecNGS) is rapidly emerging as a valuable, highly sensitive and accurate method for detecting and characterizing mutations in any cell type, tissue or organism from which...
5.
Cho E, Swartz C, Williams A, Rivas M, Recio L, Witt K, et al.
Mutat Res Genet Toxicol Environ Mutagen
. 2023 Jul;
889:503649.
PMID: 37491114
Error-corrected duplex sequencing (DS) enables direct quantification of low-frequency mutations and offers tremendous potential for chemical mutagenicity assessment. We investigated the utility of DS to quantify induced mutation frequency (MF)...
6.
Smith-Roe S, Hobbs C, Hull V, Auman J, Recio L, Streicker M, et al.
bioRxiv
. 2023 May;
PMID: 37214853
Highlights: DuplexSeq is an ultra-accurate NGS technology that directly quantifies mutationsENU-dependent mutagenesis was detected 24 h post-exposure in proliferative tissuesMultiple tissues exhibited the canonical ENU mutation spectrum 7 d after...
7.
Smith-Roe S, Swartz C, Rashid A, Christy N, Sly J, Chang X, et al.
Environ Mol Mutagen
. 2023 Mar;
64(4):202-233.
PMID: 36880770
Glyphosate, the most heavily used herbicide world-wide, is applied to plants in complex formulations that promote absorption. The National Toxicology Program reported in 1992 that glyphosate, administered to rats and...
8.
Marchetti F, Cardoso R, Chen C, Douglas G, Elloway J, Escobar P, et al.
Nat Rev Drug Discov
. 2023 Jan;
22(3):165-166.
PMID: 36646809
No abstract available.
9.
Smith-Roe S, Garantziotis S, Church R, Bemis J, Torous D, Shepard K, et al.
Environ Mol Mutagen
. 2022 Nov;
63(8-9):389-399.
PMID: 36323641
Black cohosh (BC; Actaea racemosa L.), a top-selling botanical dietary supplement, is marketed to women primarily to ameliorate a variety of gynecological symptoms. Due to widespread usage, limited safety information,...
10.
Ooka M, Zhao J, Shah P, Travers J, Klumpp-Thomas C, Xu X, et al.
Arch Toxicol
. 2022 Apr;
96(7):1975-1987.
PMID: 35435491
Currently, approximately 80,000 chemicals are used in commerce. Most have little-to-no toxicity information. The U.S. Toxicology in the 21st Century (Tox21) program has conducted a battery of in vitro assays...