Visual Function and Pattern Visual Evoked Response in Optic Neuritis

Overview

Journal Br J Ophthalmol

Specialty Ophthalmology

Date 1987 Aug 1

PMID 3651376

Citations 12

Authors

E A Sanders

A C Volkers

J C van der Poel

G H Van Lith

Affiliations

Soon will be listed here.

Abstract

The disparity between clinical visual function and pattern visual evoked response (VER) was studied in 53 patients who had suffered an attack of optic neuritis (ON) more than six months before. The visual functions tested included Snellen visual acuity, colour vision, visual field, and contrast sensitivity. The effect of pattern presentation, check size, and luminance was tested by recording VERs with several stimulus configurations. VER amplitudes were found to be associated with the outcome of all four clinical tests, independently of check size, luminance, or the presentation method used. On the other hand VER latencies were hardly ever related to the results of any of the four clinical visual tests. These findings support the idea that VER amplitude provides information about visual spatial perception, while VER latency is more related to the extent of demyelination.

Citing Articles

Multifocal visual evoked potential in optic neuritis, ischemic optic neuropathy and compressive optic neuropathy.

Jayaraman M, Gandhi R, Ravi P, Sen P Indian J Ophthalmol. 2013; 62(3):299-304.

PMID: 24088641 PMC: 4061667. DOI: 10.4103/0301-4738.118452.

Prospective, cross-sectional study, demonstrating efficacy of blue fixation target while recording Pattern Visual Evoked Potential in optic neuropathy.

Vincent A, Shetty R, Kurian M, Shetty B Doc Ophthalmol. 2009; 119(2):89-99.

PMID: 19513771 DOI: 10.1007/s10633-009-9174-9.

VEP vernier, VEP grating, and behavioral grating acuity in patients with cortical visual impairment.

Watson T, Orel-Bixler D, Haegerstrom-Portnoy G Optom Vis Sci. 2009; 86(6):774-80.

PMID: 19390471 PMC: 3862531. DOI: 10.1097/OPX.0b013e3181a59d2a.

Measurement of the retinal nerve fibre layer with scanning laser polarimetry in patients with previous demyelinating optic neuritis.

Steel D, Waldock A J Neurol Neurosurg Psychiatry. 1998; 64(4):505-9.

PMID: 9576544 PMC: 2170052. DOI: 10.1136/jnnp.64.4.505.

Comparison of Snellen acuity and objective assessment using the spatial frequency sweep PVER.

Arai M, KATSUMI O, Paranhos F, Lopes de Faria J, Hirose T Graefes Arch Clin Exp Ophthalmol. 1997; 235(7):442-7.

PMID: 9248841 DOI: 10.1007/BF00947064.

References

Cobb W, Morton H, Ettlinger G . Cerebral potentials evoked by pattern reversal and their suppression in visual rivalry. Nature. 1967; 216(5120):1123-5. DOI: 10.1038/2161123b0. View

Bradley W, Whitty C . Acute optic neuritis: its clinical features and their relation to prognosis for recovery of vision. J Neurol Neurosurg Psychiatry. 1967; 30(6):531-8. PMC: 496244. DOI: 10.1136/jnnp.30.6.531. View

Richey E, Kooi K, Tourtellotte W . Visually evoked responses in multiple sclerosis. J Neurol Neurosurg Psychiatry. 1971; 34(3):275-80. PMC: 1083464. DOI: 10.1136/jnnp.34.3.275. View

Halliday A, McDonald W, Mushin J . Delayed visual evoked response in optic neuritis. Lancet. 1972; 1(7758):982-5. DOI: 10.1016/s0140-6736(72)91155-5. View

CAMPBELL F, Maffei L . Contrast and spatial frequency. Sci Am. 1974; 231(5):106-14. DOI: 10.1038/scientificamerican1174-106. View

HERON J, Regan D, Milner B . Delay in visual perception in unilateral optic atrophy after retrobulbar neuritis. Brain. 1974; 97(1):69-78. DOI: 10.1093/brain/97.1.69. View

Asselman P, Chadwick D, Marsden D . Visual evoked responses in the diagnosis and management of patients suspected of multiple sclerosis. Brain. 1975; 98(2):261-82. DOI: 10.1093/brain/98.2.261. View

Regan D, Milner B, HERON J . Delayed visual perception and delayed visual evoked potentials in the spinal form of multiple sclerosis and in retrobulbar neuritis. Brain. 1976; 99(1):43-66. DOI: 10.1093/brain/99.1.43. View

Ellenberger Jr C, Ziegler S . Visual evoked potentials and quantitative perimetry in multiple sclerosis. Ann Neurol. 1977; 1(6):561-4. DOI: 10.1002/ana.410010608. View

10.

Regan D, Silver R, Murray T . Visual acuity and contrast sensitivity in multiple sclerosis--hidden visual loss: an auxiliary diagnostic test. Brain. 1977; 100(3):563-79. DOI: 10.1093/brain/100.3.563. View

11.

Nilsson B . Visual evoked responses in multiple sclerosis: comparison of two methods for pattern reversal. J Neurol Neurosurg Psychiatry. 1978; 41(6):499-504. PMC: 493076. DOI: 10.1136/jnnp.41.6.499. View

12.

Bodis-Wollner I, HENDLEY C, Mylin L, Thornton J . Visual evoked potentials and the visuogram in multiple sclerosis. Ann Neurol. 1979; 5(1):40-7. DOI: 10.1002/ana.410050107. View

13.

Zimmern R, CAMPBELL F, WILKINSON I . Subtle disturbances of vision after optic neuritis elicited by studying contrast sensitivity. J Neurol Neurosurg Psychiatry. 1979; 42(5):407-12. PMC: 490227. DOI: 10.1136/jnnp.42.5.407. View

14.

Keemink C, van der Wildt G, van Deursen J . Microprocessor-controlled contrast sensitivity measurements. Med Biol Eng Comput. 1979; 17(3):371-8. DOI: 10.1007/BF02443825. View

15.

Patterson V, HERON J . Visual field abnormalities in multiple sclerosis. J Neurol Neurosurg Psychiatry. 1980; 43(3):205-9. PMC: 490511. DOI: 10.1136/jnnp.43.3.205. View

16.

Kirkham T, Coupland S . Multiple regression analysis of diagnostic predictors in optic nerve disease. Can J Neurol Sci. 1981; 8(1):67-72. DOI: 10.1017/s0317167100042876. View

17.

Gawel M, Das P, Vincent S, ROSE F . Visual and auditory evoked responses in patients with Parkinson's disease. J Neurol Neurosurg Psychiatry. 1981; 44(3):227-32. PMC: 490897. DOI: 10.1136/jnnp.44.3.227. View

18.

Braddick O . Spatial frequency analysis in vision. Nature. 1981; 291(5810):9-11. DOI: 10.1038/291009a0. View

19.

Riemslag F, Spekreijse H, van Walbeek H . Pattern evoked potential diagnosis of multiple sclerosis: a comparison of various contrast stimuli. Adv Neurol. 1982; 32:417-26. View

20.

Regan D, Bartol S, Murray T, Beverley K . Spatial frequency discrimination in normal vision and in patients with multiple sclerosis. Brain. 1982; 105 (Pt 4):735-54. DOI: 10.1093/brain/105.4.735. View