Influence of a Twofold Voluntary Hyperventilation on Visually Evoked Cortical Potentials and Human Pupillogram

Overview

Journal Doc Ophthalmol

Specialty Ophthalmology

Date 1991 Jan 1

PMID 1760970

Citations 2

Authors

V S Gavriysky

Affiliations

Soon will be listed here.

Abstract

We studied the direct and aftereffects of twofold hyperventilation (HV) on pattern reversing VEPs and pupillograms (PGs) of 19 healthy volunteers. The VEP-N80 and P100 latencies increased during HV. Both peak times were maintained for a longer period, up to 20 minutes after HV-2 ended. In addition, the PG-latency time during HV and the PG-construction time during and after HV were increased. The results indicated a temporary delay of neural afferent transmission in the visual system during and after HV. A similar delay of the nervous transmission appeared in the efferent part of the system regulating the pupillary movements after HV ended. The observed changes of the VEP and PG parameters most probably resulted from the hypocapnia cased by HV and its effect on the brain vessels, although other explanations for the changes of the VEP- and PG-parameters may have been possible.

Citing Articles

Inconclusive evidence that breathing shapes pupil dynamics in humans: a systematic review.

Schaefer M, Edwards S, Norden F, Lundstrom J, Arshamian A Pflugers Arch. 2022; 475(1):119-137.

PMID: 35871662 PMC: 9816272. DOI: 10.1007/s00424-022-02729-0.

Changes in visual-evoked potential habituation induced by hyperventilation in migraine.

Coppola G, Curra A, Sava S, Alibardi A, Parisi V, Pierelli F J Headache Pain. 2010; 11(6):497-503.

PMID: 20625915 PMC: 3476226. DOI: 10.1007/s10194-010-0239-7.

References

Davies H, Carroll W, Mastaglia F . Effects of hyperventilation on pattern-reversal visual evoked potentials in patients with demyelination. J Neurol Neurosurg Psychiatry. 1986; 49(12):1392-6. PMC: 1029124. DOI: 10.1136/jnnp.49.12.1392. View

Cluff R . Chronic hyperventilation and its treatment by physiotherapy: discussion paper. J R Soc Med. 1984; 77(10):855-62. PMC: 1440257. DOI: 10.1177/014107688407701011. View

Grunberger J, Linzmayer L, Cepko H, Saletu B . [Pupillometry in psychopharmacologic experiments]. Arzneimittelforschung. 1986; 36(1):141-6. View

Albrecht H, Bruhn R, Lorenz D, Lucker P, Schumacher M . [Pupillometry: a non-invasive pharmacokinetic and pharmacodynamic method to study the action of trospium chloride (Spasmo-lyt) on smooth muscle]. Methods Find Exp Clin Pharmacol. 1983; 5(8):585-7. View

DRISCHEL H . [Studies on the dynamics of the photoreflex of the human pupil. I. The normal reflex process after short illumination and its variability]. Pflugers Arch Gesamte Physiol Menschen Tiere. 1957; 264(2):145-68. DOI: 10.1007/BF00363403. View

Araki S, Murata K, Aono H . Central and peripheral nervous system dysfunction in workers exposed to lead, zinc and copper. A follow-up study of visual and somatosensory evoked potentials. Int Arch Occup Environ Health. 1987; 59(2):177-87. DOI: 10.1007/BF00378495. View

George D, Nutt D, Walker W, Porges S, Adinoff B, Linnoila M . Lactate and hyperventilation substantially attenuate vagal tone in normal volunteers. A possible mechanism of panic provocation?. Arch Gen Psychiatry. 1989; 46(2):153-6. DOI: 10.1001/archpsyc.1989.01810020055009. View

Yamazaki H . Pattern visual evoked cortical potential waveforms and spatial frequency characteristics in children. Doc Ophthalmol. 1988; 70(1):59-65. DOI: 10.1007/BF00154736. View

Sanders E, Volkers A, van der Poel J, Van Lith G . Visual function and pattern visual evoked response in optic neuritis. Br J Ophthalmol. 1987; 71(8):602-8. PMC: 1041240. DOI: 10.1136/bjo.71.8.602. View

10.

Alexandridis E, Krastel H, Reuther R . [To what extent does impairment of the pupil light response occur in cortical blindness?]. Fortschr Ophthalmol. 1983; 80(1):79-81. View

11.

Ohtsuka K, Asakura K, Kawasaki H, Sawa M . Respiratory fluctuations of the human pupil. Exp Brain Res. 1988; 71(1):215-7. DOI: 10.1007/BF00247537. View

12.

Kraaier V, van Huffelen A, Wieneke G . Changes in quantitative EEG and blood flow velocity due to standardized hyperventilation; a model of transient ischaemia in young human subjects. Electroencephalogr Clin Neurophysiol. 1988; 70(5):377-87. DOI: 10.1016/0013-4694(88)90015-6. View