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The Ultrastructure of the Nervous Tissue in a Benign Teratoma

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Specialty Neurology
Date 1987 Jan 1
PMID 3618120
Citations 2
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Abstract

The ultrastructure of the nervous tissue in a benign ovarian teratoma is described. This tissue was organized into areas having both "meningeal" and "ependymal" surfaces, between which were found astrocytes, ependymal cells, neurones with synapses and microglia. These cells all had ultrastructural similarities to their normal counterparts in the nervous system. In addition, some signs of degenerative change--due possibly to the abnormal location of the nervous tissue--were observed. Oligodendrocytes and myelin were absent, possibly because of vascular insufficiency.

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An immunohistochemical study of neuropeptides and neuronal cytoskeletal proteins in the neuroepithelial component of a spontaneous murine ovarian teratoma. Primitive neuroepithelium displays immunoreactivity for neuropeptides and neuron-associated....

Caccamo D, Herman M, Frankfurter A, Katsetos C, Collins V, Rubinstein L Am J Pathol. 1989; 135(5):801-13.

PMID: 2817080 PMC: 1880094.


Microglial and neural differentiation in human teratomas.

Sangruchi T, Sobel R Acta Neuropathol. 1989; 78(3):258-63.

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References
1.
Trojanowski J, Hickey W . Human teratomas express differentiated neural antigens. An immunohistochemical study with anti-neurofilament, anti-glial filament, and anti-myelin basic protein monoclonal antibodies. Am J Pathol. 1984; 115(3):383-9. PMC: 1900511. View

2.
Kennedy C, Grave G, Jehle J, Sokoloff L . Blood flow to white matter during maturation of the brain. Neurology. 1970; 20(6):613-8. DOI: 10.1212/wnl.20.6.613. View

3.
Pappas C . CNS myelin and synapses in a spontaneous mouse ovarian teratoma showing neural differentiation. An immunohistochemical and electron microscopic study. J Neuropathol Exp Neurol. 1981; 40(3):289-97. DOI: 10.1097/00005072-198105000-00007. View

4.
Herman M, Sipe J, Rubinstein L, Vandenberg S, Spence A, VRAA-JENSEN J . An experimental mouse testicular teratoma as a model for neuroepithelial neoplasia and differentiation. II. Electron microscopy. Am J Pathol. 1975; 81(2):421-44. PMC: 2032223. View

5.
Use S, VIETTI T . Ovarian teratoma. Ultrastructure and neural component. Cancer. 1968; 21(1):38-52. DOI: 10.1002/1097-0142(196801)21:1<38::aid-cncr2820210108>3.0.co;2-l. View