Arctigenin: Pharmacology, Total Synthesis, and Progress in Structure Modification

Overview

Journal J Enzyme Inhib Med Chem

Specialty Biochemistry

Date 2022 Sep 12

PMID 36093586

Authors

Dan Wu

Lili Jin

Xing Huang

Hao Deng

Qing-Kun Shen

Zhe-Shan Quan

Changhao Zhang

Hong-Yan Guo

Affiliations

Soon will be listed here.

Abstract

is a prevalent medicinal herb and a health supplement that is commonly used in Asia. Over the last few decades, the bioactive component arctigenin has attracted the attention of researchers because of its anti-inflammatory, antioxidant, immunomodulatory, multiple sclerosis fighting, antitumor, and anti-leukemia properties. After summarising the research and literature on arctigenin, this study outlines the current status of research on pharmacological activity, total synthesis, and structural modification of arctigenin. The purpose of this study is to assist academics in obtaining a more comprehensive understanding of the research progress on arctigenin and to provide constructive suggestions for further investigation of this useful molecule.

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