Spinal Paget's Disease with Bilevel Cord Compression and Ischemic Non-compressive Myelopathy Treated with Zoledronic Acid

Overview

Journal Clin Case Rep

Date 2022 Aug 24

PMID 35999985

Authors

Afef Feki

Imen Sellami

Zouhour Gassara

Samar Ben Djemaa

Mariam Ezzeddine

Mohamed Hedi Kallel

Hela Fourati

Rim Akrout

Sofien Baklouti

Affiliations

Soon will be listed here.

Abstract

Cord compression and ischemic non-compressive myelopathy are a complication of spinal Paget's disease (SPD). SPD usually touches a single spine level. We report an unusual case with bilevel spinal cord compression and dysfunction which was medically treated due to resolution of the vascular steal syndrome.

Citing Articles

Surgical decompression in spinal Paget's disease: illustrative case.

Price A, File C, Call-Orellana F, Andrade de Almeida R, North R J Neurosurg Case Lessons. 2024; 8(4).

PMID: 39038367 PMC: 11284652. DOI: 10.3171/CASE24203.

Newly Diagnosed Monostotic Paget's Disease of Bone during Living Kidney Donor Candidate Evaluation.

Jedrzejuk D, Poznanski P, Szewczyk P, Mazanowska O, Bolanowski M, Krajewska M Biomedicines. 2023; 11(2).

PMID: 36830939 PMC: 9953426. DOI: 10.3390/biomedicines11020401.

Spinal Paget's disease with bilevel cord compression and ischemic non-compressive myelopathy treated with zoledronic acid.

Feki A, Sellami I, Gassara Z, Ben Djemaa S, Ezzeddine M, Kallel M Clin Case Rep. 2022; 10(8):e6263.

PMID: 35999985 PMC: 9388838. DOI: 10.1002/ccr3.6263.

References

Zhao Y, Wang Y, Qiu G, Shen J, Weng X, Li X . A case of thoracic spinal stenosis secondary to Paget's disease. Chin Med Sci J. 2010; 25(2):125-8. DOI: 10.1016/s1001-9294(10)60035-1. View

Gomez Cerezo J, Martinez Garcia F, Lopez Rodriguez M, Fernandez Tajuelo R, Barbado Hernandez F, Vazquez Munoz E . [Progressive paraparesis and background of Paget's disease]. Rev Clin Esp. 2006; 206(8):403-4. DOI: 10.1157/13090512. View

Boutin R, Spitz D, Newman J, Lenchik L, Steinbach L . Complications in Paget disease at MR imaging. Radiology. 1998; 209(3):641-51. DOI: 10.1148/radiology.209.3.9844654. View

Pestka J, Seitz S, Zustin J, Puschel K, Amling M, Barvencik F . Paget disease of the spine: an evaluation of 101 patients with a histomorphometric analysis of 29 cases. Eur Spine J. 2012; 21(5):999-1006. PMC: 3337908. DOI: 10.1007/s00586-011-2133-7. View

Saifuddin A, Hassan A . Paget's disease of the spine: unusual features and complications. Clin Radiol. 2003; 58(2):102-11. DOI: 10.1053/crad.2002.1152. View

Eekhoff M, van der Klift M, Kroon H, Cooper C, Hofman A, Pols H . Paget's disease of bone in The Netherlands: a population-based radiological and biochemical survey--the Rotterdam Study. J Bone Miner Res. 2004; 19(4):566-70. DOI: 10.1359/jbmr.2004.19.4.566. View

Gennari L, Rendina D, Falchetti A, Merlotti D . Paget's Disease of Bone. Calcif Tissue Int. 2019; 104(5):483-500. DOI: 10.1007/s00223-019-00522-3. View

Altman R . Musculoskeletal manifestations of Paget's disease of bone. Arthritis Rheum. 1980; 23(10):1121-7. DOI: 10.1002/art.1780231008. View

Beaudouin C, Dohan A, Nasrallah T, Parlier C, Touraine S, Ea K . Atypical vertebral Paget's disease. Skeletal Radiol. 2014; 43(7):991-5. DOI: 10.1007/s00256-013-1799-9. View

10.

Tan L, Kasliwal M, Harbhajanka A, Miller I, Deutsch H . Malignant degeneration of multilevel monostotic Paget's disease involving the thoracic spine: an unusual presentation. J Clin Neurosci. 2014; 21(7):1254-6. DOI: 10.1016/j.jocn.2013.11.003. View

11.

Britton C, Walsh J . Paget disease of bone - an update. Aust Fam Physician. 2012; 41(3):100-3. View

12.

Zuckerman S, Mocco J . Response. Neurosurg Focus. 2013; 34(4):E11. DOI: 10.3171/2013.4.FOC-LSRSabstracts. View

13.

Alaya R, Alaya Z, Nang M, Bouajina E . [Paget's disease of bone: Diagnostic and therapeutic updates]. Rev Med Interne. 2017; 39(3):185-191. DOI: 10.1016/j.revmed.2017.05.010. View

14.

Singer F, Bone 3rd H, Hosking D, Lyles K, Murad M, Reid I . Paget's disease of bone: an endocrine society clinical practice guideline. J Clin Endocrinol Metab. 2014; 99(12):4408-22. DOI: 10.1210/jc.2014-2910. View

15.

Chen J, Rhee R, Wallach S, Avramides A, Flores A . Neurologic disturbances in Paget disease of bone: response to calcitonin. Neurology. 1979; 29(4):448-57. DOI: 10.1212/wnl.29.4.448. View

16.

Browne C, Mutsaers A, Fisher B . A Case of Mistaken Identity: Paget's Disease of the Bone Causing Cord Compression-Case Report and Review of the Literature. Pract Radiat Oncol. 2019; 9(6):e613-e619. DOI: 10.1016/j.prro.2019.06.015. View

17.

Hepple S, Getty J, Douglas D . Paget's disease and odontoid peg fracture: a case report. Injury. 1998; 29(4):323-5. DOI: 10.1016/s0020-1383(98)80034-x. View

18.

Hadjipavlou A, Gaitanis L, Katonis P, Lander P . Paget's disease of the spine and its management. Eur Spine J. 2001; 10(5):370-84. PMC: 3611523. DOI: 10.1007/s005860100329. View

19.

Zlatkin M, Lander P, Hadjipavlou A, Levine J . Paget disease of the spine: CT with clinical correlation. Radiology. 1986; 160(1):155-9. DOI: 10.1148/radiology.160.1.2940618. View

20.

Cicuttini F, Baro G, Littlejohn G . Paget's disease of the thoracic spine. A case report. Australas Radiol. 1990; 34(2):177-80. DOI: 10.1111/j.1440-1673.1990.tb02840.x. View