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Extracellular Vesicles, Inflammation, and Cardiovascular Disease

Overview
Journal Cells
Publisher MDPI
Date 2022 Jul 27
PMID 35883672
Authors
Affiliations
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Abstract

Cardiovascular disease is a leading cause of death worldwide. The underlying mechanisms of most cardiovascular disorders involve innate and adaptive immune responses, and extracellular vesicles are implicated in both. In this review, we describe the mechanistic role of extracellular vesicles at the intersection of inflammatory processes and cardiovascular disease. Our discussion focuses on atherosclerosis, myocardial ischemia and ischemic heart disease, heart failure, aortic aneurysms, and valvular pathology.

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