The Emergence of Nanoporous Materials in Lung Cancer Therapy

Overview

Journal Sci Technol Adv Mater

Specialty Biomedical Engineering

Date 2022 Jul 25

PMID 35875329

Authors

Deepika Radhakrishnan

Shan Mohanan

Goeun Choi

Jin-Ho Choy

Steffi Tiburcius

Hoang Trung Trinh

Shankar Bolan

Nikki Verrills

Pradeep Tanwar

Ajay Karakoti

Ajayan Vinu

Affiliations

Soon will be listed here.

Abstract

Lung cancer is one of the most common cancers, affecting more than 2.1 million people across the globe every year. A very high occurrence and mortality rate of lung cancer have prompted active research in this area with both conventional and novel forms of therapies including the use of nanomaterials based drug delivery agents. Specifically, the unique physico-chemical and biological properties of porous nanomaterials have gained significant momentum as drug delivery agents for delivering a combination of drugs or merging diagnosis with targeted therapy for cancer treatment. This review focuses on the emergence of nano-porous materials for drug delivery in lung cancer. The review analyses the currently used nanoporous materials, including inorganic, organic and hybrid porous materials for delivering drugs for various types of therapies, including chemo, radio and phototherapy. It also analyses the selected research on stimuli-responsive nanoporous materials for drug delivery in lung cancer before summarizing the various findings and projecting the future of emerging trends. This review provides a strong foundation for the current status of the research on nanoporous materials, their limitations and the potential for improving their design to overcome the unique challenges of delivering drugs for the treatment of lung cancer.

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