Early Disseminated Mycobacterium Abscessus Complex Infection in an Infant with Coexisting Cystic Fibrosis and Progressive Familial Intrahepatic Cholestasis: Case Report and Literature Review

Overview

Journal Sultan Qaboos Univ Med J

Specialty General Medicine

Date 2022 Jun 8

PMID 35673280

Authors

Sanjeewani A Weerakoon

Maya Al Salti

Jalila Mohsin

Hilal Al Hashami

Tawfiq Al Lawati

Hussain Mohsin

Affiliations

Soon will be listed here.

Abstract

(MABSC) is a rapidly growing and may rarely cause disseminated infections in immunocompromised patients. In patients with cystic fibrosis (CF), it peaks between the ages of 11 and 15 years. We present a five-month-old infant with coexisting CF and progressive familial intrahepatic cholestasis (PFIC) who had pulmonary and cutaneous dissemination of MABSC infection. The management of this disseminated infection in an infant with two coexisting chronic diseases was challenging and resulted in the rapid deterioration of lung function and progression of PFIC to liver cirrhosis with a fatal outcome.

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