Nontuberculous Mycobacterial Disease in Childhood - Update on Diagnostic Approaches and Treatment
Overview
Affiliations
Recent studies suggest that the incidence of nontuberculous mycobacterial infections in children may be increasing. Nontuberculous mycobacterial lymphadenitis, skin and soft tissue infection, and pulmonary disease each present unique challenges in relation to diagnosis and treatment. In this update, we critically review the recent literature on the epidemiology, clinical features, diagnostic approaches and treatment of nontuberculous mycobacterial disease in children. In addition, we outline key areas warranting further research.
A 28-Year Multicenter Cohort Study of Nontuberculous Mycobacterial Lymphadenitis in Children, Spain.
Martinez-Planas A, Baquero-Artigao F, Mendez-Echevarria A, Del Rosal T, Rodriguez-Molino P, Toro-Rueda C Emerg Infect Dis. 2025; 31(3):536-546.
PMID: 40023802 PMC: 11878309. DOI: 10.3201/eid3103.241254.
Cinicola B, Ottaviano G, Hashim I, Zainudeen Z, Hamid I, Elfeky R J Clin Immunol. 2023; 44(1):23.
PMID: 38129624 PMC: 10739425. DOI: 10.1007/s10875-023-01615-3.
Tsumura Y, Muramatsu H, Tetsuka N, Imaizumi T, Sato K, Inoue K Haematologica. 2023; 109(9):2988-2997.
PMID: 37881854 PMC: 11367237. DOI: 10.3324/haematol.2023.283636.
Challenging diagnosis of infection: A case report and literature review.
Grupel D, Sagi O, Nissan I, Grossman R, Yair M, Moran-Gilad J J Clin Tuberc Other Mycobact Dis. 2023; 33:100393.
PMID: 37637323 PMC: 10450513. DOI: 10.1016/j.jctube.2023.100393.
Weerakoon S, Al Salti M, Mohsin J, Al Hashami H, Al Lawati T, Mohsin H Sultan Qaboos Univ Med J. 2022; 22(2):295-299.
PMID: 35673280 PMC: 9155037. DOI: 10.18295/squmj.6.2021.089.