» Articles » PMID: 23347634

Rapidly Growing Mycobacterial Bloodstream Infections

Overview
Date 2013 Jan 26
PMID 23347634
Citations 57
Authors
Affiliations
Soon will be listed here.
Abstract

About 20 species of rapidly growing mycobacteria species that are capable of infecting human beings and causing bloodstream infections have been identified. Many more of these species are being discovered worldwide, especially in resource-poor settings. These microorganisms have been known to cause outbreaks and pseudo-outbreaks. Although rapidly growing mycobacteria are not highly virulent or life threatening, they have a high predisposition to create biofilms and to colonise and infect intravascular catheters. Early detection and identification of specific species can help to estimate predictable antimicrobial susceptibility patterns. However, because susceptibility data originate from developed countries, studies in resource-poor settings urgently need to be done. The best outcome of cure without recurrence depends on a combination of at least 4 weeks of treatment with two or more active antimicrobial agents, plus removal of the intravascular catheter. We review and discuss the epidemiology, pathogenesis, diagnosis, management, and outcomes of rapidly growing mycobacterial bloodstream infections.

Citing Articles

Systematic literature review of the diagnosis, prognosis, and treatment of peritoneal dialysis-related infection caused by nontuberculous mycobacteria.

Kadota N, Ishikawa K, Kubono Y, Konishi K, Fujimaru T, Ito Y BMC Nephrol. 2024; 25(1):432.

PMID: 39609738 PMC: 11606208. DOI: 10.1186/s12882-024-03841-2.


Progressive lower extremity cellulitis in a patient with systemic lupus erythematosus on systemic immunosuppression: A rare manifestation of cutaneous tuberculosis.

Alam M, Fitzpatrick T, DeNiro K, Simmons J, LaCourse S JAAD Case Rep. 2024; 53:17-22.

PMID: 39430636 PMC: 11488445. DOI: 10.1016/j.jdcr.2024.08.007.


catheter-related bloodstream infection in an immunocompetent patient: A case report and review of the literature.

Turock J, Matysiak Match C, Adachi K, Nielsen-Saines K, Yang S, Malhotra S IDCases. 2024; 37:e02051.

PMID: 39193404 PMC: 11347832. DOI: 10.1016/j.idcr.2024.e02051.


Mycobacterial Biofilm: Mechanisms, Clinical Problems, and Treatments.

Liu X, Hu J, Wang W, Yang H, Tao E, Ma Y Int J Mol Sci. 2024; 25(14).

PMID: 39063012 PMC: 11277187. DOI: 10.3390/ijms25147771.


Formative evaluation and structural analysis of non-tuberculosis mycobacterial biofilm using material pieces.

Yamamoto K, Torigoe S, Kobayashi H Cell Surf. 2024; 11:100125.

PMID: 38799511 PMC: 11126951. DOI: 10.1016/j.tcsw.2024.100125.