Truncal Fat and Frailty Are Important Predictors of Cognitive Performance Among Aging Adults with Obesity

Overview

Journal J Nutr Health Aging

Specialties Geriatrics
Nutritional Sciences

Date 2022 May 19

PMID 35587753

Authors

H D Heisey

M E Kunik

C Qualls

M B Segoviano-Escobar

D T Villareal

Affiliations

Soon will be listed here.

Abstract

Objectives: To explore associations among cognition, frailty, and obesity in older adults.

Design: Descriptive, secondary analysis of baseline data from two related lifestyle intervention trials.

Setting: Clinical study open to civilian population through the Center for Translational Research on Inflammatory Diseases at the Veterans Affairs Medical Center in Houston, TX.

Participants: One hundred eight community-dwelling adults with obesity, aged 65 or older, recruited consecutively from two lifestyle intervention trials.

Measurements: Cognition was assessed using Composite Age-Adjusted Scale Score from the National Institutes of Health Toolbox Cognition Battery: Obesity was assessed by body mass index (BMI) and also by truncal fat mas via dual energy x-ray absorptiometry. Frailty was assessed using the Physical Performance Test.

Results: A significant linear regression model for cognition revealed frailty as the strongest predictor, followed by sex, and then truncal fat (R2=0.340, p<0.001).

Conclusion: Cognition among community-dwelling older adults with obese BMI may worsen with greater truncal fat mass. Frailty appears to be an important predictor of cognitive performance in this population.

Citing Articles

Correlation between fat-to-muscle mass ratio and cognitive impairment in elderly patients with type 2 diabetes mellitus: a cross-sectional study.

Wu F, Liu Y, Lin C, Haghbin N, Xia L, Li Y BMC Geriatr. 2024; 24(1):352.

PMID: 38637745 PMC: 11027286. DOI: 10.1186/s12877-024-04941-2.

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