Comprehensive Evaluation of Probiotic Property, Hypoglycemic Ability and Antioxidant Activity of Lactic Acid Bacteria

Overview

Journal Foods

Specialty Biotechnology

Date 2022 May 14

PMID 35564086

Authors

Hongyu Wang

Liang Li

Affiliations

Soon will be listed here.

Abstract

Taking lactic acid bacteria is an important strategy to alleviate or prevent diabetes, but the candidate strains with good genetic stability and excellent functions still need to be supplemented. In this study, the hypoglycemic ability (α-amylase, α-glucosidase and dipeptidyl peptidase 4), probiotic property and antioxidant activity of lactic acid bacteria were comprehensively evaluated by a principal component analysis (PCA) and analytic hierarchy process (AHP). The results showed that ) had a higher survival rate (82.78%) in gastric juice and good tolerance to bile salt, and can be colonized in HT-29 cells. had a remarkable inhibitive activity of α-amylase (82.21%), α-glucosidase (84.29%) and dipeptidyl peptidase 4 (42.51%). had better scavenging activity of free radicals, total antioxidant activity (FRAP) and superoxide dismutase activity. According to the scores of the PCA, had the best hypoglycemic ability, and () had the highest probiotic property. According to AHP, was the best potential hypoglycemic probiotic; furthermore, showed the highest comprehensive performance except . All lactic acid bacteria in this test had good safety. is expected to become a new potential hypoglycemic strain.

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